Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 2/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 8/20 | 0.36 |
| ▸ | SCN4A | P35499 | 4/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | F12 | P00748 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7100197 | 0.84 | PARP1 (0.35) | SMARCA2SMARCA4PBRM1SCN3ASCN4A | |
| SCHEMBL25081186 | 0.71 | SMARCA2 (0.46) | SMARCA2SMARCA4PBRM1SCN3ASCN4A | |
| SCHEMBL31525447 | 0.67 | PTPN1 (0.41) | SCN3ASCN4ASCN9AHSP90AA1HSP90AB1 | |
| SCHEMBL7103436 | 0.67 | P2RX3 (0.36) | SMARCA2SMARCA4PBRM1SCN9APARP1 | |
| SCHEMBL24176885 | 0.63 | PARP1 (0.36) | SMARCA2SMARCA4PBRM1HSP90AA1HSP90AB1 | |
| SCHEMBL18007742 | 0.63 | SCN3A (0.50) | SMARCA2SMARCA4PBRM1SCN3ASCN4A | |
| SCHEMBL29887044 | 0.63 | GPR119 (0.43) | SCN3ASCN9AHSP90AA1HSP90AB1SCN5A | |
| SCHEMBL21964515 | 0.63 | L3MBTL1 (0.46) | SCN3ASCN4ASCN9AHSP90AA1HSP90AB1 | |
| SCHEMBL256728 | 0.62 | UCHL1 (0.51) | GPR119 | |
| SCHEMBL21055656 | 0.61 | ACLY (0.47) | SCN3ASCN4ASCN9AHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030073850-A1 | 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use | ABBOTT LABORATORIES | 2003-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073850-A1 | 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use | ADRA1D, ADRB1, ADRA1A | SMARCA2 638/4885SMARCA4 583/4885PBRM1 960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.