Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700370 | 0.83 | DUSP5 (0.31) | — | |
| SCHEMBL11630075 | 0.81 | — | — | |
| SCHEMBL7101512 | 0.76 | TTR (0.31) | — | |
| SCHEMBL7103268 | 0.75 | TTR (0.30) | — | |
| SCHEMBL700371 | 0.68 | TTR (0.31) | — | |
| SCHEMBL7103287 | 0.67 | PKLR (0.36) | — | |
| Water SCHEMBL31493916 | 0.63 | — | — | |
| SCHEMBL2192826 | 0.63 | HTR2A (0.33) | — | |
| SCHEMBL28898922 | 0.59 | DUSP5 (0.44) | — | |
| SCHEMBL29497714 | 0.58 | PKLR (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0965580-B1 | Method for producing 1,2-Naphthoquinone-2-diazide derivative | TOYO GOSEI KOGYO KK (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6077941-A | Method for producing 1,2-naphthoquinone-2-diazide derivatives | TOYO GOSEI KOGYO CO., LTD. (JP) | 2000-06-20 | — | — | US | disclosed |
| EP-0965580-A1 | Method for producing 1,2-Naphthoquinone-2-diazide derivative | Toyo Gosei Kogyo Co., Ltd. (JP) | 1999-12-22 | — | — | EP | disclosed |