Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.33 |
| ▸ | TUBB | P07437 | 3/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7113750 | 0.75 | SMPD3 (0.44) | SMPD3PDPK1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7111056 | 0.74 | CLK4 (0.37) | — | |
| SCHEMBL7114096 | 0.74 | ADRA1A (0.36) | SMPD3PDPK1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7110942 | 0.73 | PDPK1 (0.40) | SMPD3PDPK1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7109779 | 0.71 | ECE1 (0.40) | SMPD3PDPK1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7446349 | 0.69 | KDM4E (0.42) | CYP1A2RAB9A | |
| SCHEMBL5396495 | 0.68 | ADRA1D (0.52) | SMPD3PDPK1CYP1A2ECE1TUBB4A | |
| SCHEMBL29715238 | 0.68 | ADRA1D (0.52) | SMPD3PDPK1CYP1A2ECE1TUBB4A | |
| SCHEMBL7451095 | 0.68 | SMPD3 (0.40) | SMPD3PDPK1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7107722 | 0.67 | TUBB4A (0.36) | SMPD3PDPK1CYP1A1CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030008901-A1 | Hydroxy pipecolate hydroxamic acid derivatives | MCCLURE KIM F (US) | 2003-01-09 | — | — | US | disclosed |
| US-20020019534-A1 | Gem substituted hydroxamic acids | PFIZER INC. | 2002-02-14 | — | — | US | disclosed |
| EP-1104403-A1 | HYDROXY PIPECOLATE HYDROXAMIC ACID DERIVATIVES AS MMP INHIBITORS | Pfizer Products Inc. (US) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009485-A1 | HYDROXY PIPECOLATE HYDROXAMIC ACID DERIVATIVES AS MMP INHIBITORS | PFIZER PRODUCTS INC. (US) | 2000-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019534-A1 | Gem substituted hydroxamic acids | MMP14, TOP2A, ADAMTS1 | SMPD3 849/4885PDPK1 3966/4885CYP1A1 1477/4885 |
| US-20030008901-A1 | Hydroxy pipecolate hydroxamic acid derivatives | MMP1, MMP10, MMP3 | SMPD3 1542/4885PDPK1 3673/4885CYP1A1 3130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.