SCHEMBL710802

SCHEMBL710802

COc1ccccc1[PH](=O)C(=O)c1c(C)cc(C)cc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.44
KMT2A Q03164 3/20 0.42
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.40
HSD17B10 Q99714 1/20 0.40
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KCNMA1 Q12791 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
PKM P14618 1/20 0.37
MAPT P10636 3/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
IDO1 P14902 1/20 0.36
TDO2 P48775 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28061700 0.88 CA12 (0.43) KMT2AMEN1GAAHSD17B10ALDH1A1
SCHEMBL425864 0.87 ABCB1 (0.39) ABCB1KMT2AMEN1GAAHSD17B10
SCHEMBL710598 0.85 THRB (0.41) KMT2AGAAHSD17B10ALDH1A1KCNMA1
SCHEMBL155285 0.85 IRAK4 (0.40) ABCB1KMT2AMEN1ALDH1A1LMNA
SCHEMBL28049109 0.83 ALDH1A1 (0.40) KMT2AMEN1GAAALDH1A1SMN1; SMN2
SCHEMBL28200325 0.83 LMNA (0.36) KMT2AMEN1ALDH1A1SMN1; SMN2LMNA
SCHEMBL7175680 0.79 HPGD (0.40) GAAHSD17B10ALDH1A1SMN1; SMN2PKM
SCHEMBL29877185 0.78 LMNA (0.39) KMT2AMEN1SMN1; SMN2MAPTLMNA
SCHEMBL27762470 0.78 CA12 (0.46) ABCB1KMT2AMEN1GAAALDH1A1
SCHEMBL29044846 0.77 RAPGEF4 (0.37) KMT2AMEN1GAAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102811695-B One-pack dental adhesive material composition KURARAY NORITAKE DENTAL INC 2015-01-07 CN claimed
EP-2226060-B1 CEMENT FOR DENTAL APPLICATIONS KURARAY NORITAKE DENTAL INC (JP) 2020-03-04 EP disclosed
CN-110317226-A Silane coupling compound and medical courses in general curable composition for dental applications containing them 株式会社松风 2019-10-11 CN disclosed
CN-110093122-A The manufacturing method of adhesive composition, bonding sheet and adhesive 赛登化学株式会社 2019-08-06 CN disclosed
CN-110072948-A METHOD FOR PRODUCING SURFACE-TREATED COLORED INORGANIC PARTICLES 可乐丽则武齿科株式会社 2019-07-30 CN disclosed
CN-109803989-A Optical stereo moulding composition 可乐丽则武齿科株式会社 2019-05-24 CN disclosed
CN-106102691-B Dental composition 登特斯普伊德特雷有限公司 2019-03-15 CN disclosed
CN-105792794-B Dental composition 登特斯普伊德特雷有限公司 2019-03-15 CN disclosed
CN-105164216-B Inkjet ink composition, ink jet recording method, ink group, decoration sheet and molding, mould internal shaping product and its manufacture method 富士胶片株式会社 2017-09-22 CN disclosed
CN-106456452-A Self-adhesive dental composite resin 可乐丽则武齿科株式会社 2017-02-22 CN disclosed
CN-102341088-A Curable composition for dental use and composite resin using same KURARAY MEDICAL INC 2012-02-01 CN disclosed
CN-101605524-B Dental composition KURARAY MEDICAL INC. (JP) 2011-12-28 CN disclosed
CN-102083403-A Dental composition and composite resin KURARAY MEDICAL INC 2011-06-01 CN disclosed
CN-102014848-A Dental composition and composite resin KURARAY MEDICAL INC 2011-04-13 CN disclosed
CN-102014847-A Dental composition and composite resin KURARAY MEDICAL INC 2011-04-13 CN disclosed
US-20110003267-A1 DENTAL COMPOSITION KURARAY MEDICAL INC. (JP) 2011-01-06 US disclosed
CN-101909579-A Cement for dental applications KURARAY MEDICAL INC 2010-12-08 CN disclosed
US-20100267856-A1 CEMENT FOR DENTAL APPLICATIONS KURARAY MEDICAL INC. (JP) 2010-10-21 US disclosed
EP-2226060-A1 CEMENT FOR DENTAL APPLICATIONS Kuraray Medical Inc. (JP) 2010-09-08 EP disclosed
CN-101605524-A Dental composition KURARAY MEDICAL INC (JP) 2009-12-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110003267-A1 DENTAL COMPOSITION NLRP3, TAS2R42, CAD ABCB1 1449/4885KMT2A 973/4885MEN1 4418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.