SCHEMBL710948

SCHEMBL710948

c1ccc(NCc2nccc(-c3ccc(-c4ccc(N(c5ccccc5)c5ccccc5)cc4)cc3)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.38
MAOB P27338 3/20 0.38
CAMK2D Q13557 3/20 0.38
TRPV3 Q8NET8 2/20 0.37
SREBF2 Q12772 1/20 0.36
MAPK8 P45983 2/20 0.36
PIK3CG P48736 2/20 0.36
GSK3B P49841 2/20 0.36
CAMKK2 Q96RR4 2/20 0.36
CYP11B1 P15538 1/20 0.36
KCNH3 Q9ULD8 1/20 0.36
JAK2 O60674 1/20 0.36
JAK3 P52333 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TP53 P04637 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL710577 0.96 SREBF2 (0.38) MAOAMAOBCAMK2DTRPV3SREBF2
SCHEMBL709040 0.88 CYP2C9 (0.38) CAMK2DTRPV3SREBF2GSK3BCYP11B1
SCHEMBL710850 0.77 CAMK2D (0.63) CAMK2DMAPK8PIK3CGGSK3BCAMKK2
SCHEMBL710949 0.74 AURKA (0.40) CYP11B1JAK2KDM4EALDH1A1CYP1A2
SCHEMBL709831 0.73 IKBKB (0.59) CAMK2DMAPK8PIK3CGGSK3BCAMKK2
SCHEMBL712182 0.73 HSP90AA1 (0.69) GSK3BJAK3KDM4EALDH1A1CYP1A2
SCHEMBL708351 0.72 DYRK1A (0.48) CAMK2DGSK3BJAK3CYP1A2AURKA
SCHEMBL10019585 0.71 DYRK1A (0.49) CAMK2DGSK3BCYP11B1TP53CYP1A2
SCHEMBL709817 0.70 CTSK (0.43) CYP11B1KDM4EALDH1A1TP53CYP1A2
SCHEMBL10019584 0.70 DYRK1A (0.48) GSK3BCYP11B1TP53CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124762-B2 Diphenyl amine derivatives having luminescence property KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2012-02-28 US disclosed
US-20100063281-A1 DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2010-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100063281-A1 DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY TYR, PNMT, DDC MAOA 15/4885MAOB 13/4885CAMK2D 2043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.