Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Squaric Acid Dibutyl Ester SCHEMBL56180 | 0.86 | CYP3A4 (0.44) | ALDH1A1LMNAKDM4EMAPTNPSR1 | |
| SCHEMBL9809602 | 0.79 | THRA (0.44) | THRATHRBCYP3A4TSHRMAPK1 | |
| SCHEMBL14557648 | 0.79 | LTA4H (0.41) | ALDH1A1LMNAKDM4EMAPTNPSR1 | |
| SCHEMBL8646943 | 0.78 | ALDH1A1 (0.37) | ALDH1A1LMNAKDM4EMAPTNPSR1 | |
| SCHEMBL9809623 | 0.77 | THRA (0.46) | ALDH1A1LMNATHRATHRBTSHR | |
| SCHEMBL26278001 | 0.77 | THRA (0.46) | ALDH1A1LMNATHRATHRBTSHR | |
| SCHEMBL26278000 | 0.77 | THRA (0.46) | ALDH1A1LMNATHRATHRBTSHR | |
| SCHEMBL9809630 | 0.77 | THRA (0.46) | ALDH1A1LMNATHRATHRBTSHR | |
| SCHEMBL9809613 | 0.77 | THRA (0.46) | ALDH1A1LMNATHRATHRBTSHR | |
| SCHEMBL6658770 | 0.77 | THRA (0.46) | ALDH1A1LMNATHRATHRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9841428-B2 | Viscosity-sensitive dyes and method | SETA BIOMEDICALS, LLC (US) | 2017-12-12 | — | — | US | disclosed |
| US-9744245-B2 | Oligosaccharide conjugates and methods of use | The Secretary of State for Environment Food and Rural Affairs (GB) | 2017-08-29 | — | — | US | disclosed |
| US-20170210764-A1 | CYCLOBUTENEDIONE DERIVATIVE, NONAQUEOUS ELECTROLYTIC SOLUTION, AND LITHIUM ION SECONDARY BATTERY | NEC CORPORATION (JP) | 2017-07-27 | — | — | US | disclosed |
| US-20160091495-A1 | VISCOSITY-SENSITIVE DYES AND METHOD | SETA BIOMEDICALS, LLC | 2016-03-31 | — | — | US | disclosed |
| US-20160067345-A1 | OLIGOSACCHARIDE CONJUGATES AND METHODS OF USE | THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS (GB) | 2016-03-10 | — | — | US | disclosed |
| US-8940911-B2 | Squarylated lactones inhibitors for bacterial biofilm formation | SYRACUSE UNIVERSITY (US) | 2015-01-27 | — | — | US | disclosed |
| US-20140039195-A1 | Squarylated Lactones Inhibitors for Bacterial Biofilm Formation | SYRACUSE UNIVERSITY (US) | 2014-02-06 | — | — | US | disclosed |
| WO-2003087052-A2 | DYES AND FLUORESCENT COMPOUNDS | TERPETSCHNIG EWALD A (US) | 2003-10-23 | — | — | WO | disclosed |
| US-6482950-B1 | Squarylium compounds, and processes and intermediates for the synthesis of these compounds | POLAROID CORPORATION | 2002-11-19 | — | — | US | disclosed |
| US-5919950-A | SYNTHESIS OF SQUARATE DYES | POLAROID CORPORATION (US) | 1999-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210764-A1 | CYCLOBUTENEDIONE DERIVATIVE, NONAQUEOUS ELECTROLYTIC SOLUTION, AND LITHIUM ION SECONDARY BATTERY | HSD17B11, HSD17B7, HSD17B2 | ALDH1A1 894/4885LMNA 2294/4885KDM4E 2582/4885 |
| US-20160067345-A1 | OLIGOSACCHARIDE CONJUGATES AND METHODS OF USE | FUT6, SI, DDOST | ALDH1A1 2421/4885LMNA 3295/4885KDM4E 1511/4885 |
| US-20140039195-A1 | Squarylated Lactones Inhibitors for Bacterial Biofilm Formation | BPHL, MGLL, FDFT1 | ALDH1A1 3229/4885LMNA 4117/4885KDM4E 2577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.