Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | BRAF | P15056 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550314 | 0.89 | KDM4E (0.51) | GAASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL1026723 | 0.89 | BRAF (0.56) | GAASMN1; SMN2BRAFHDAC1HDAC3 | |
| SCHEMBL7765927 | 0.86 | KDM4E (0.58) | BRAFHDAC1ALDH1A1MAPTKDM4E | |
| SCHEMBL7765911 | 0.85 | XDH (0.55) | GAASMN1; SMN2HDAC8ALDH1A1MAPT | |
| SCHEMBL7765105 | 0.85 | MMP13 (0.49) | GAAALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL7118203 | 0.83 | GAA (0.53) | GAABRAFHDAC1HDAC3HDAC4 | |
| SCHEMBL1403643 | 0.82 | GAA (0.72) | GAAALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL8008958 | 0.81 | POLB (0.55) | SMN1; SMN2ALDH1A1KDM4ETDP1CYP1A2 | |
| SCHEMBL11574967 | 0.81 | POLB (0.55) | SMN1; SMN2ALDH1A1KDM4ETDP1CYP1A2 | |
| SCHEMBL1027039 | 0.81 | TDP1 (0.61) | GAASMN1; SMN2BRAFHDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030186944-A1 | Such as 4-(2-(3-dimethylaminobenzoylamino)phenoxy)phthalic acid for treatment/prevention of diabetes; for inhibiting liver glycogen phosphorylase; dietetics | KRISTIANSEN MARIT (DK) | 2003-10-02 | — | — | US | disclosed |
| US-6590118-B1 | Used in treatment of and/or prevention of diabetes, especially non-insulin dependent diabetes (Type 2 diabetes) | NOVO NORDISK A/S (DK) | 2003-07-08 | — | — | US | disclosed |
| EP-1220832-A1 | NOVEL AROMATIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2002-07-10 | — | — | EP | disclosed |
| WO-2001023347-A1 | NOVEL AROMATIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2001-04-05 | — | — | WO | disclosed |
| EP-0255037-B1 | A METHOD FOR FORMING POLYIMIDE FILM BY CHEMICAL VAPOR DEPOSITION | HITACHI, LTD. (JP) | 1992-12-09 | — | — | EP | disclosed |
| US-4759958-A | Method for forming polyimide film by chemical vapor deposition | HITACHI, LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0255037-A2 | A method for forming polyimide film by chemical vapor deposition | HITACHI, LTD. (JP) | 1988-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186944-A1 | Such as 4-(2-(3-dimethylaminobenzoylamino)phenoxy)phthalic acid for treatment/prevention of diabetes; for inhibiting liver glycogen phosphorylase; dietetics | PYGL, GYS2, PYGM | GAA 99/4885SMN1; SMN2 3594/4885BRAF 4298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.