Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PARL | Q9H300 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14738049 | 1.00 | ACHE (0.65) | ACHEL3MBTL1HSD11B1ALDH1A1PARL | |
| SCHEMBL31173382 | 0.92 | ACHE (0.56) | ACHEL3MBTL1HSD11B1ALDH1A1PARL | |
| SCHEMBL16802348 | 0.83 | ACHE (0.69) | ACHEHSD11B1HTTRECQLSMN1; SMN2 | |
| SCHEMBL30695870 | 0.81 | ACHE (0.52) | ACHEL3MBTL1HSD11B1ALDH1A1PARL | |
| SCHEMBL22308528 | 0.81 | ACHE (0.51) | ACHEL3MBTL1HSD11B1ALDH1A1PARL | |
| SCHEMBL28453189 | 0.81 | ACHE (0.51) | ACHEL3MBTL1HSD11B1ALDH1A1PARL | |
| SCHEMBL17758627 | 0.80 | ACHE (0.51) | ACHEL3MBTL1HSD11B1ALDH1A1PARL | |
| SCHEMBL17749075 | 0.80 | ACHE (0.51) | ACHEL3MBTL1HSD11B1ALDH1A1PARL | |
| SCHEMBL6417230 | 0.79 | PARL (0.57) | ACHEHSD11B1ALDH1A1PARLHTT | |
| SCHEMBL6346703 | 0.78 | L3MBTL1 (0.67) | ACHEL3MBTL1ALDH1A1HTTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111675806-B | Air atmosphere anion ring-opening polymerization method of N-sulfonyl aziridine derivative | 上海交通大学 | 2022-01-11 | — | — | CN | claimed |
| CN-108586738-B | Synthesis method of linear polyethyleneimine segmented copolymer | 南京工业大学 | 2020-10-27 | — | — | CN | claimed |
| CN-111675806-A | Air atmosphere anion ring-opening polymerization method of N-sulfonyl aziridine derivative | 上海交通大学 | 2020-09-18 | — | — | CN | claimed |
| EP-4692057-A1 | NOVEL B0AT1 INHIBITOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2026-02-11 | — | — | EP | disclosed |
| US-20260001849-A1 | NOVEL B0AT1 INHIBITOR | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2026-01-01 | — | — | US | disclosed |
| CN-118834153-A | 5-Substituted indoline chiral amine, preparation method thereof and application thereof in preparation of silodosin | 浙江大学 | 2024-10-25 | — | — | CN | disclosed |
| WO-2024210198-A1 | NOVEL B0AT1 INHIBITOR | 田辺三菱製薬株式会社 | 2024-10-10 | — | — | WO | disclosed |
| CN-111675806-B | Air atmosphere anion ring-opening polymerization method of N-sulfonyl aziridine derivative | 上海交通大学 | 2022-01-11 | — | — | CN | disclosed |
| CN-108586738-B | Synthesis method of linear polyethyleneimine segmented copolymer | 南京工业大学 | 2020-10-27 | — | — | CN | disclosed |
| CN-111675806-A | Air atmosphere anion ring-opening polymerization method of N-sulfonyl aziridine derivative | 上海交通大学 | 2020-09-18 | — | — | CN | disclosed |
| EP-2763990-B1 | PYRROLOPYRAZINE KINASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2017-02-22 | — | — | EP | disclosed |
| EP-2763990-A1 | PYRROLOPYRAZINE KINASE INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2014-08-13 | — | — | EP | disclosed |
| US-8658646-B2 | Pyrrolopyrazine kinase inhibitors | HOFFMANN-LAROCHE INC. (US) | 2014-02-25 | — | — | US | disclosed |
| WO-2013030138-A1 | PYRROLOPYRAZINE KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-03-07 | — | — | WO | disclosed |
| US-20130059834-A1 | PYRROLOPYRAZINE KINASE INHIBITORS | HOFFMANN-LA ROCHE INC. | 2013-03-07 | — | — | US | disclosed |
| US-6620824-B2 | Process for the synthesis of gonadotropin releasing hormone antagonists | MERCK & CO., INC. | 2003-09-16 | — | — | US | disclosed |
| US-20030013876-A1 | Process for the synthesis of gonadotropin releasing hormone antagonists | MERCK & CO., INC. | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260001849-A1 | NOVEL B0AT1 INHIBITOR | BCAT1, BCAT2, BHMT | ACHE 4709/4885L3MBTL1 72/4885HSD11B1 610/4885 |
| US-20130059834-A1 | PYRROLOPYRAZINE KINASE INHIBITORS | SYK, ZAP70, JAK1 | ACHE 4796/4885L3MBTL1 4588/4885HSD11B1 2927/4885 |
| US-20030013876-A1 | Process for the synthesis of gonadotropin releasing hormone antagonists | GNRHR, FSHR, GHRHR | ACHE 2781/4885L3MBTL1 4866/4885HSD11B1 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.