Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920539 | 0.79 | HTR1A (0.50) | SIGMAR1OPRM1 | |
| SCHEMBL29538605 | 0.78 | HDAC8 (0.49) | SIGMAR1HRH2 | |
| SCHEMBL6920302 | 0.77 | HDAC8 (0.53) | SIGMAR1OPRM1MEN1GAAKMT2A | |
| SCHEMBL6919160 | 0.77 | OPRM1 (0.51) | OPRM1 | |
| SCHEMBL32677229 | 0.75 | OPRM1 (0.37) | OPRM1HTR2A | |
| SCHEMBL28301774 | 0.74 | LMNA (0.43) | SIGMAR1OPRM1 | |
| SCHEMBL29538848 | 0.74 | LMNA (0.43) | SIGMAR1OPRM1 | |
| SCHEMBL6820388 | 0.73 | HDAC8 (0.48) | — | |
| SCHEMBL17231981 | 0.73 | SIGMAR1 (0.49) | SIGMAR1HRH2MEN1APAF1GAA | |
| SCHEMBL29538556 | 0.71 | ADORA2A (0.44) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004041816-A1 | AZACYCLIC COMPOUNDS AS OREXIN RECEPTOR ANTAGONIST | GLAXO GROUP LIMITED (GB) | 2004-05-21 | — | — | WO | disclosed |