Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711097 | 0.89 | — | — | |
| SCHEMBL711059 | 0.77 | APP (0.39) | APP | |
| SCHEMBL13528703 | 0.73 | — | — | |
| SCHEMBL712047 | 0.70 | APP (0.38) | APP | |
| SCHEMBL712121 | 0.70 | APP (0.38) | APP | |
| SCHEMBL9784645 | 0.70 | — | — | |
| Water SCHEMBL713364 | 0.69 | APP (0.37) | APP | |
| SCHEMBL711464 | 0.68 | AGXT (0.35) | APP | |
| SCHEMBL712557 | 0.67 | AGXT (0.33) | APP | |
| SCHEMBL717265 | 0.67 | CA2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040564-B2 | Stabilized composition | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-05-26 | — | — | US | disclosed |
| US-9040564-B2 | Stabilized composition | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-05-26 | — | — | US | disclosed |
| US-8124780-B2 | Benzimidazole compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-02-28 | — | — | US | disclosed |
| US-8124780-B2 | Benzimidazole compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-02-28 | — | — | US | disclosed |
| US-20110009624-A9 | BENZIMIDAZOLE COMPOUNDS HAVING GASTRIC ACID SECRETION INHIBITORY ACTION | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-01-13 | — | — | US | disclosed |
| US-20110009624-A9 | BENZIMIDAZOLE COMPOUNDS HAVING GASTRIC ACID SECRETION INHIBITORY ACTION | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-01-13 | — | — | US | disclosed |
| EP-1870409-B1 | BENZIMIDAZOLE COMPOUNDS | EISAI R&D MAN CO LTD (JP) | 2010-05-12 | — | — | EP | disclosed |
| EP-1870409-B1 | BENZIMIDAZOLE COMPOUNDS | EISAI R&D MAN CO LTD (JP) | 2010-05-12 | — | — | EP | disclosed |
| US-20100022778-A1 | PROCESS FOR PRODUCTION OF SULFINYLBENZIMIDAZOLE COMPOUNDS OR SALTS THEREOF | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-01-28 | — | — | US | disclosed |
| US-20100022778-A1 | PROCESS FOR PRODUCTION OF SULFINYLBENZIMIDAZOLE COMPOUNDS OR SALTS THEREOF | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-01-28 | — | — | US | disclosed |
| US-20080145421-A1 | A layer of a benzamidazole-proton pump inhibitor and ethyl celluose is coated on an inert or basic material core material; an exterior layer of enteric polymer to prevent the dissolution of the drug in the stomach but in the intestines; storage stability; time-release agents; gastrointestinal disorders | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-06-19 | — | — | US | disclosed |
| WO-2008047849-A1 | PROCESS FOR THE PRODUCTION OF 2- [ [4- T (2, 2-DIMETHYL-1, 3-DIOXAN-5-YL) METHOXY] PYRIDIN-2-YL] METHYLTHIO] -1H-BENZIMIDAZOLE | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2008-04-24 | — | — | WO | disclosed |
| WO-2008047849-A1 | PROCESS FOR THE PRODUCTION OF 2- [ [4- T (2, 2-DIMETHYL-1, 3-DIOXAN-5-YL) METHOXY] PYRIDIN-2-YL] METHYLTHIO] -1H-BENZIMIDAZOLE | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2008-04-24 | — | — | WO | disclosed |
| EP-1875911-A1 | STABILIZED COMPOSITION | Eisai R&D Management Co., Ltd. (JP) | 2008-01-09 | — | — | EP | disclosed |
| EP-1870409-A1 | BENZIMIDAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-12-26 | — | — | EP | disclosed |
| EP-1870409-A1 | BENZIMIDAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-12-26 | — | — | EP | disclosed |
| US-20070015782-A1 | Benzimidazole compound | EISAI CO., LTD. | 2007-01-18 | — | — | US | disclosed |
| US-20070015782-A1 | Benzimidazole compound | EISAI CO., LTD. | 2007-01-18 | — | — | US | disclosed |
| US-20070010542-A1 | Benzimidazole compound | EISAI CO., LTD. | 2007-01-11 | — | — | US | disclosed |
| US-20070010542-A1 | Benzimidazole compound | EISAI CO., LTD. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080145421-A1 | A layer of a benzamidazole-proton pump inhibitor and ethyl celluose is coated on an inert or basic material core material; an exterior layer of enteric polymer to prevent the dissolution of the drug in the stomach but in the intestines; storage stability; time-release agents; gastrointestinal disorders | SI, CEL, PGA5 | APP 4435/4885 |
| US-20110009624-A9 | BENZIMIDAZOLE COMPOUNDS HAVING GASTRIC ACID SECRETION INHIBITORY ACTION | GIPR, HRH2, SI | APP 4618/4885 |
| US-20070010542-A1 | Benzimidazole compound | HRH2, GIPR, HRH4 | APP 4883/4885 |
| US-20070015782-A1 | Benzimidazole compound | HRH2, GIPR, HRH4 | APP 4883/4885 |
| US-20100022778-A1 | PROCESS FOR PRODUCTION OF SULFINYLBENZIMIDAZOLE COMPOUNDS OR SALTS THEREOF | SULT1E1, SULT1A1, SQOR | APP 4572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.