Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 3/20 | 0.58 |
| ▸ | HTR1D | P28221 | 2/20 | 0.58 |
| ▸ | HTR1B | P28222 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.58 |
| ▸ | HTR7 | P34969 | 2/20 | 0.58 |
| ▸ | HTR6 | P50406 | 2/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | HTR1E | P28566 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11401246 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2HTR2AHTR1DHTR1BHTR2C | |
| SCHEMBL14665073 | 0.85 | HTR2A (0.67) | SMN1; SMN2HTR2AHTR1DHTR1BHTR2C | |
| SCHEMBL1911320 | 0.85 | HTR2A (0.66) | SMN1; SMN2HTR2AHTR1DHTR1BHTR2C | |
| SCHEMBL357990 | 0.85 | HTR2A (0.66) | SMN1; SMN2HTR2AHTR1DHTR1BHTR2C | |
| SCHEMBL9279873 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2HTR2AHTR1DHTR1BHTR2C | |
| SCHEMBL7848453 | 0.83 | ALDH1A1 (0.67) | SMN1; SMN2HTR2AHTR1DHTR1BHTR2C | |
| SCHEMBL7421069 | 0.82 | HTR2A (0.62) | SMN1; SMN2HTR2AHTR1DHTR1BHTR2C | |
| Tryptophanol SCHEMBL29401346 | 0.81 | HTR2A (0.71) | SMN1; SMN2HTR2AHTR1DHTR1BHTR2C | |
| Tryptophanol SCHEMBL143812 | 0.81 | HTR2A (0.71) | SMN1; SMN2HTR2AHTR1DHTR1BHTR2C | |
| Tryptophanol SCHEMBL81822 | 0.81 | HTR2A (0.71) | SMN1; SMN2HTR2AHTR1DHTR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55081859-A | — | — | None | — | — | JP | disclosed |
| JP-55081859-A | — | — | None | — | — | JP | disclosed |
| JP-55162992-A | — | — | None | — | — | JP | disclosed |
| US-12331020-B2 | Method of synthesizing indole compounds | 1280225 B.C. LTD. (CA) | 2025-06-17 | — | — | US | disclosed |
| CN-116891821-B | Culture medium for co-culture of trichoderma asperellum HG1 and bacillus subtilis Tpb55 and biocontrol agent thereof | 中国农业科学院烟草研究所 | 2024-06-07 | — | — | CN | disclosed |
| US-20240059653-A1 | METHOD OF SYNTHESIZING INDOLE COMPOUNDS | 1280225 B.C. LTD. (CA) | 2024-02-22 | — | — | US | disclosed |
| CN-116891821-A | Culture medium for co-culture of trichoderma asperellum HG1 and bacillus subtilis Tpb55 and biocontrol agent thereof | 中国农业科学院烟草研究所 | 2023-10-17 | — | — | CN | disclosed |
| US-20190292149-A1 | ARYL SUBSTITUTED INDOLES AND THE USE THEREOF | PURDUE PHARMA LP (US) | 2019-09-26 | — | — | US | disclosed |
| US-20030065146-A1 | Monomeric diols, phosphate linked oligomers formed therefrom and processes for preparing | COOK PHILLIP D (US) | 2003-04-03 | — | — | US | disclosed |
| US-6448373-B1 | INHIBITORS OF ENZYMES SUCH AS PHOSPHOLIPASE A2; TREATMENT OF INFLAMMATORY DISEASES INCLUDING ATOPIC DERMATITIS AND INFLAMMATORY BOWEL DISEASE | ISIS PHARMACEUTICALS, INC. | 2002-09-10 | — | — | US | disclosed |
| EP-0739351-B1 | MONOMERIC DIOLS AND PHOSPHATE LINKED OLIGOMERS FORMED THEREFROM | ISIS PHARMACEUTICALS INC (US) | 2002-04-10 | — | — | EP | disclosed |
| US-6008398-A | Non-nucleotide phosphorus ester oligomers | GENZYME CORPORATION (US) | 1999-12-28 | — | — | US | disclosed |
| US-5919965-A | Non-nucleotide phosphorus ester oligomers | GENZYME CORPORATION (US) | 1999-07-06 | — | — | US | disclosed |
| US-5886177-A | ETHYLENE GLYCOL MONOMERS JOINED VIA STANDARD PHOSPHATE LINKAGES INCLUDING PHOSPHOROTHIOATE, PHOSPHODIESTER, AND PHOSPHORAMIDATE LINKAGES; USEFUL FUNCTIONAL GROUPS INCLUDE NUCLEOBASES AS WELL AS POLAR GROUPS, HYDROPHOBIC GROUPS | ISIS PHARMACEUTICALS, INC. (US) | 1999-03-23 | — | — | US | disclosed |
| EP-0739351-A4 | MONOMERIC DIOLS AND PHOSPHATE LINKED OLIGOMERS FORMED THEREFROM | ISIS PHARMACEUTICALS INC (US) | 1998-10-21 | — | — | EP | disclosed |
| EP-0739351-A1 | MONOMERIC DIOLS AND PHOSPHATE LINKED OLIGOMERS FORMED THEREFROM | ISIS PHARMACEUTICALS, INC. (US) | 1996-10-30 | — | — | EP | disclosed |
| WO-1995018820-A1 | MONOMERIC DIOLS AND PHOSPHATE LINKED OLIGOMERS FORMED THEREFROM | ISIS PHARMACEUTICALS, INC. (US) | 1995-07-13 | — | — | WO | disclosed |
| JP-S55162992-A | PREPARATION OF L-TRYPTOPHAN | MICROBIAL CHEM RES FOUND | 1980-12-18 | — | — | JP | disclosed |
| JP-S5581859-A | 3-(2,3-DIHYDROXYPROPYL)INDOLE AND ITS PREPARATION | MICROBIAL CHEM RES FOUND | 1980-06-20 | — | — | JP | disclosed |
| JP-S5581859-A | 3-(2,3-DIHYDROXYPROPYL)INDOLE AND ITS PREPARATION | MICROBIAL CHEM RES FOUND | 1980-06-20 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240059653-A1 | METHOD OF SYNTHESIZING INDOLE COMPOUNDS | IDO1, TPH1, TPH2 | SMN1; SMN2 3987/4885HTR2A 27/4885HTR1D 18/4885 |
| US-20190292149-A1 | ARYL SUBSTITUTED INDOLES AND THE USE THEREOF | TRPC5, TRPV5, TRPV1 | SMN1; SMN2 1471/4885HTR2A 223/4885HTR1D 88/4885 |
| US-12331020-B2 | Method of synthesizing indole compounds | IDO1, TPH1, TPH2 | SMN1; SMN2 3987/4885HTR2A 27/4885HTR1D 18/4885 |
| US-20030065146-A1 | Monomeric diols, phosphate linked oligomers formed therefrom and processes for preparing | BPGM, PPIP5K2, PGM2 | SMN1; SMN2 3732/4885HTR2A 4406/4885HTR1D 4213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.