SCHEMBL715432

SCHEMBL715432

O=C1c2cc([N+](=O)[O-])cc([N+](=O)[O-])c2-c2c1ccc([N+](=O)[O-])c2[N+](=O)[O-]

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HKDC1 Q2TB90 1/20 0.53
S100A4 P26447 4/20 0.46
PTPRC P08575 3/20 0.46
HPRT1 P00492 1/20 0.44
TRPV1 Q8NER1 1/20 0.43
BCHE P06276 2/20 0.42
ACHE P22303 2/20 0.42
CES1 P23141 2/20 0.42
ALDH1A1 P00352 4/20 0.41
CYP3A4 P08684 3/20 0.41
CYP1A2 P05177 2/20 0.41
HIF1A Q16665 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TSHR P16473 1/20 0.41
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
GPR35 Q9HC97 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TP53 P04637 1/20 0.39
CYP2D6 P10635 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29413348 1.00 HKDC1 (0.53) HKDC1S100A4PTPRCHPRT1TRPV1
SCHEMBL11334260 0.88 HKDC1 (0.47) HKDC1S100A4PTPRCHPRT1TRPV1
SCHEMBL8973490 0.87 BCHE (0.53) S100A4PTPRCTRPV1BCHEACHE
SCHEMBL74588 0.87 HKDC1 (0.65) HKDC1S100A4PTPRCHPRT1TRPV1
SCHEMBL29435119 0.87 HKDC1 (0.65) HKDC1S100A4PTPRCHPRT1TRPV1
SCHEMBL11518981 0.83 S100A4 (0.61) HKDC1S100A4PTPRCHPRT1TRPV1
SCHEMBL6378793 0.83 S100A4 (0.69) HKDC1S100A4PTPRCBCHEACHE
SCHEMBL29413355 0.81 S100A4 (0.62) HKDC1S100A4PTPRCHPRT1TRPV1
SCHEMBL6924564 0.81 PTPRC (0.58) HKDC1S100A4PTPRCHPRT1TRPV1
SCHEMBL55362 0.81 S100A4 (0.62) HKDC1S100A4PTPRCHPRT1TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 378 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5213923-A PHOTOSENSITIVE MATERIAL FOR ELECTROPHOTOGRAPHY COMPRISING A CHARGE TRANSPORT LAYER COMPRISING AN ORGANOPOLYSILANE AND DIPHENOQUINONE MITA INDUSTRIAL CO., LTD. (JP) 1993-05-25 US claimed
US-4551404-A AZO PIGMENT, CHARGE TRANSFER MULTILAYER ELEMENT CANON KABUSHIKI KAISHA (JP) 1985-11-05 US claimed
US-20260140457-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR KYOCERA DOCUMENT SOLUTIONS INC (JP) 2026-05-21 US disclosed
US-20260104655-A1 IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC (JP) 2026-04-16 US disclosed
US-20260099103-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC (JP) 2026-04-09 US disclosed
US-12578662-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2026-03-17 US disclosed
US-20260064022-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC (JP) 2026-03-05 US disclosed
EP-4685565-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA Document Solutions Inc. (JP) 2026-01-28 EP disclosed
EP-4685564-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD FOR MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMATION DEVICE KYOCERA Document Solutions Inc. (JP) 2026-01-28 EP disclosed
EP-4664200-A1 IMAGE FORMING APPARATUS Kyocera Document Solutions Inc. (JP) 2025-12-17 EP disclosed
US-20250377605-A1 IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2025-12-11 US disclosed
EP-0506492-A2 Benzidine derivative and photosensitive material using said derivate MITA INDUSTRIAL CO. LTD. (JP) 1992-09-30 EP disclosed
EP-0506493-A2 Phenylenediamine derivative and photosensitive material using said derivative MITA INDUSTRIAL CO. LTD. (JP) 1992-09-30 EP disclosed
US-5087544-A PERYLENE ELECTROPHOTOSENSITIVE MATERIAL WITH M-PHENYLENEDIAMINE MITA INDUSTRIAL CO., LTD. (JP) 1992-02-11 US disclosed
EP-0455247-A2 m-Phenylenediamine compound and electrophotosensitive material using said compound MITA INDUSTRIAL CO. LTD. (JP) 1991-11-06 EP disclosed
EP-0426445-A2 Photosensitive material for electrophotography MITA INDUSTRIAL CO. LTD. (JP) 1991-05-08 EP disclosed
US-5004662-A Having increased sensitivity and mobility MITA INDUSTRIAL CO., LTD. (JP) 1991-04-02 US disclosed
EP-0390195-A1 Electrophotosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1990-10-03 EP disclosed
US-4123270-A PRIMARY AMINE SOLUBLE DISAZO AND SQUARIC ACID DERIVATIVE DYES INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1978-10-31 US disclosed
US-4030923-A Mixture of binder materials for use in connection with a charge transport layer in a photoconductor INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1977-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260099103-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS NR2E3, ASIC3, GJB2 HKDC1 4795/4885S100A4 1504/4885PTPRC 3583/4885
US-12578662-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus RPP30, RPA3, SERPINB10 HKDC1 4189/4885S100A4 602/4885PTPRC 3633/4885
US-20260104655-A1 IMAGE FORMING APPARATUS DSG1, MARK4, SMC4 HKDC1 4294/4885S100A4 746/4885PTPRC 3891/4885
US-20260140457-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR CRY1, GJB2, ALDH1A2 HKDC1 4048/4885S100A4 1719/4885PTPRC 4424/4885
US-20260064022-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS NR2E3, DDT, ITGAL HKDC1 4704/4885S100A4 4480/4885PTPRC 2435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.