Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RHOC | P08134 | 1/20 | 0.45 |
| ▸ | RHOA | P61586 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1875367 | 0.85 | L3MBTL1 (0.73) | L3MBTL1NPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL712088 | 0.85 | L3MBTL1 (0.63) | L3MBTL1NPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL20981664 | 0.84 | L3MBTL1 (0.82) | L3MBTL1NPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL10277409 | 0.83 | L3MBTL1 (0.61) | L3MBTL1NPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL5545392 | 0.79 | L3MBTL1 (0.65) | L3MBTL1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2104422 | 0.78 | RAB9A (0.69) | NPC1RAB9AMAPTRHOCRHOA | |
| SCHEMBL7194329 | 0.78 | RAB9A (0.56) | L3MBTL1NPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL2328579 | 0.77 | ALDH1A1 (0.59) | L3MBTL1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL826360 | 0.77 | L3MBTL1 (0.67) | L3MBTL1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL5546915 | 0.77 | L3MBTL1 (0.67) | L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6590123-B2 | For cancer theapy | MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY | 2003-07-08 | — | — | US | disclosed |
| US-20020022747-A1 | Aminobenzoic acid derivatives having anti-tumorigenic activity, methods of making and using the same | BEKESI GEORGE J (US) | 2002-02-21 | — | — | US | disclosed |
| US-6294695-B1 | HALOACETOAMIDOBENZOYLUREAS OR ETHYL HALOACETOAMIDOBENZOATES | MOUNT SINAI SCHOOL OF MEDICINE OF THE CITY UNIVERSITY OF NEW YORK | 2001-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020022747-A1 | Aminobenzoic acid derivatives having anti-tumorigenic activity, methods of making and using the same | ABAT, DDC, GABBR2 | L3MBTL1 759/4885NPC1 3799/4885RAB9A 2444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.