Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.31 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL11335155 | 0.95 | TDP1 (0.40) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL29913440 | 0.84 | SLC22A6 (0.35) | TDP1SMN1; SMN2SLC22A6GABRR1CA2 | |
| SCHEMBL31745565 | 0.78 | TDP1 (0.42) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL9004945 | 0.76 | MEN1 (0.30) | MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL31265939 | 0.76 | TDP1 (0.40) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL26983125 | 0.75 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL10698540 | 0.75 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL10698543 | 0.75 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL11360544 | 0.75 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL9777404 | 0.75 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848937-B | Biodegradable polyester with high gas barrier property and preparation method and application thereof | 浙江大学 | 2021-06-29 | — | — | CN | disclosed |
| CN-111848937-A | Biodegradable polyester with high gas barrier property and preparation method and application thereof | 浙江大学 | 2020-10-30 | — | — | CN | disclosed |
| US-6589324-B2 | Surface treatment solution consists of a mixture of aluminum salt and an inorganic oxide particle, an aluminum containing inorganic particle comprising aluminum, oxygen and one other element; other metal salt; phosphorus compound and a resin | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2003-07-08 | — | — | US | disclosed |
| EP-0952193-B1 | Agent for treating metallic surface, surface-treated metal material and coated metal material | TOYO BOSEKI (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-20020098345-A1 | AGENT FOR TREATING METALLIC SURFACE, SURFACE-TREATED METAL MATERIAL AND COATED METAL MATERIAL | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2002-07-25 | — | — | US | disclosed |
| EP-0952193-A1 | Agent for treating metallic surface, surface-treated metal material and coated metal material | Toyo Boseki Kabushiki Kaisha (JP) | 1999-10-27 | — | — | EP | disclosed |
| EP-0850969-A1 | Functional group terminated polymers containing sulfonate group via polymerizarion of sulfonated monomers | WITCO CORPORATION (US) | 1998-07-01 | — | — | EP | disclosed |
| EP-0849299-A1 | Polyurethane synthesis from polyesters containing sulfonate groups | WITCO CORPORATION (US) | 1998-06-24 | — | — | EP | disclosed |
| US-5530093-A | SOIL RELEASE AGENTS, ANTISTATIC AGENTS FOR TEXTILE FINISHING | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| US-5492995-A | HYDROPHILIC BLOCK POLYMER CONTAINING POLYESTER ANDPOLYSILOXANE UNITS; TEXTILE FINISHING | HOECHST AKTIENGSELLSCHAFT (DE) | 1996-02-20 | — | — | US | disclosed |
| US-5488123-A | SULFONATED; TEXTILE FINISHING; ANTISOILANTS, ANTISTATIC AGENTS | CASSELLA AG (DE) | 1996-01-30 | — | — | US | disclosed |
| US-5240780-A | Pressure sensitive adhesives | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0327763-A2 | Colored salts of polymeric sulfonate polyanions and dye cations, and light-absorbing coatings made therewith | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-08-16 | — | — | EP | disclosed |
| EP-0307867-A2 | Light-sensitive silver halide photographic material having superior sharpness and feasible for ultra-rapid processing | KONICA CORPORATION (JP) | 1989-03-22 | — | — | EP | disclosed |
| US-4250296-A | SULFO-CONTAINING POLYESTER REACTED WITH AN ETHERIFIED OR ESTERIFIED POLYOXYETHYLENE GLYCOL | CASSELLA AKTIENGESELLSCHAFT (DE) | 1981-02-10 | — | — | US | disclosed |