Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364038 | 0.87 | ALDH1A1 (0.50) | L3MBTL1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8146532 | 0.85 | ALDH1A1 (0.54) | MAPTALDH1A1HPGDALOX15CYP3A4 | |
| SCHEMBL20324688 | 0.83 | OPRM1 (0.40) | L3MBTL1MAPTRAB9AALDH1A1HPGD | |
| SCHEMBL510357 | 0.81 | ALDH1A1 (0.41) | L3MBTL1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21622784 | 0.81 | ALDH1A1 (0.55) | L3MBTL1MAPTALDH1A1HPGDALOX15 | |
| SCHEMBL1711865 | 0.81 | ALDH1A1 (0.44) | L3MBTL1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1255865 | 0.81 | LOXL2 (0.43) | RAB9ANPC1ALDH1A1HPGDALOX15 | |
| SCHEMBL21622787 | 0.81 | RAB9A (0.44) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9376259 | 0.81 | GFER (0.56) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL596315 | 0.79 | CALM1 (0.50) | L3MBTL1MAPTALDH1A1USP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4818110-B2 | — | — | 2011-11-16 | — | — | JP | claimed |
| EP-1948633-B1 | 3 -HYDROXYFLAVONE DERIVATIVES FOR THE DETECTION AND THE QUANTIFICATION OF CELL APOPTOSIS | CENTRE NAT RECH SCIENT (FR) | 2011-08-10 | — | — | EP | claimed |
| US-7880021-B2 | reacting 6-bromomethyl-4'-(diethylamino)-3-hydroxyflavone with dodecylmethylamine to form the corresponding tertiary amine (4'-(diethylamino)-6-(dodecyl(methyl)aminomethyl)-3-hydroxyflavone); and reacting the product of step a. with propansultone; use in biomembrane studies; Alzheimer's disease, cancer | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2011-02-01 | — | — | US | claimed |
| US-20090269793-A1 | Compounds and Kits for the Detection and the Quantification of Cell Apoptosis | Centre National De La Recherche Scientifiique (CNRS) | 2009-10-29 | — | — | US | claimed |
| JP-2009511566-A | — | — | 2009-03-19 | — | — | JP | claimed |
| EP-1218383-B1 | BICYCLIC IMIDAZO-5-YL-AMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2008-11-05 | — | — | EP | claimed |
| EP-1651621-B1 | 2- (QUINOXALIN-5-YLSULFONYLAMINO) -BENZAMIDE COMPOUNDS AS CCK2 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-06 | — | — | EP | claimed |
| EP-1948633-A2 | 3 -HYDROXYFLAVONE DERIVATIVES FOR THE DETECTION AND THE QUANTIFICATION OF CELL APOPTOSIS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2008-07-30 | — | — | EP | claimed |
| US-7304051-B2 | Quinoxaline compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-12-04 | — | — | US | claimed |
| US-7241759-B2 | Benzo[1,2,5]thiadiazole compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | claimed |
| US-20020183320-A1 | Bicyclic imidazo-5-yl-amine derivatives | GRUENENTHAL GMBH (DE) | 2002-12-05 | — | — | US | claimed |
| EP-1218383-A2 | BICYCLIC IMIDAZO-5-YL-AMINE DERIVATIVES | Grünenthal GmbH (DE) | 2002-07-03 | — | — | EP | claimed |
| EP-0754696-B1 | Unsymmetric diphosphine monoxide compounds and a process for preparing diphosphine compounds | TAKASAGO PERFUMERY CO LTD (JP) | 2002-01-16 | — | — | EP | claimed |
| WO-2001081344-A1 | SALTS OF BICYCLIC, N-ACYLATED IMIDAZO-3-AMINES AND IMIDAZO-5-AMINES | Grünenthal GmbH (DE) | 2001-11-01 | — | — | WO | claimed |
| WO-2001027119-A2 | SUBSTANCE LIBRARY CONTAINING BICYCLIC IMIDAZO-5-YL-AMINES AND/OR BICYCLIC IMIDAZO-3-YL-AMINES | Grünenthal GmbH (DE) | 2001-04-19 | — | — | WO | claimed |
| WO-2001027118-A2 | BICYCLIC IMIDAZO-5-YL-AMINE DERIVATIVES | Grünenthal GmbH (DE) | 2001-04-19 | — | — | WO | claimed |
| US-6117887-A | ANTIPROLIFERATIVE AGENTS | CV THERAPEUTICS, INC. (US) | 2000-09-12 | — | — | US | claimed |
| US-5808162-A | Chiral unsymmetric diphosphine compound and transition metal complex containing the same as ligand | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-09-15 | — | — | US | claimed |
| EP-0754696-A1 | Chiral unsymmetric diphosphine compounds and transition metal complexes containing them as ligands | Takasago International Corporation (JP) | 1997-01-22 | — | — | EP | claimed |
| US-4558038-A | HYPOTENSIVE AGENTS | USV PHARMACEUTICAL CORP. (US) | 1985-12-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183320-A1 | Bicyclic imidazo-5-yl-amine derivatives | ACHE, P2RX5, CNR1 | L3MBTL1 4711/4885MAPT 3783/4885RAB9A 3617/4885 |
| US-20090269793-A1 | Compounds and Kits for the Detection and the Quantification of Cell Apoptosis | BAX, CASP3, BCL2 | L3MBTL1 489/4885MAPT 4847/4885RAB9A 2451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.