SCHEMBL7199480

SCHEMBL7199480

O=S(=O)(c1ccc(Cl)cc1)c1cccc(S(=O)(=O)c2ccc(Cl)cc2)c1Cl

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.62
CYP3A4 P08684 1/20 0.62
MAPK1 P28482 1/20 0.62
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
POLB P06746 1/20 0.50
CNR2 P34972 1/20 0.49
FEN1 P39748 1/20 0.48
KDM4E B2RXH2 2/20 0.47
PKM P14618 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA3 P07451 2/20 0.46
CA4 P22748 2/20 0.46
CA6 P23280 2/20 0.46
CA5A P35218 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10869745 0.86 ALDH1A1 (0.68) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL8911211 0.85 ALDH1A1 (0.60) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL11452192 0.85 ALDH1A1 (0.60) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL28742158 0.82 ALDH1A1 (0.51) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL2034446 0.81 HSD11B1 (0.68) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL2947083 0.81 ALDH1A1 (0.60) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL10585429 0.79 POLB (0.56) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL4328031 0.78 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL22742 0.78 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL9313173 0.78 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112673051-B Polyarylene ethers 巴斯夫欧洲公司 2025-04-25 CN disclosed
US-12110368-B2 Polyarylene ether sulfone BASF SE (DE) 2024-10-08 US disclosed
US-12091503-B2 Polyarylene ether BASF SE (DE) 2024-09-17 US disclosed
EP-3850033-B1 POLYARYLENE ETHER SULFONE BASF SE (DE) 2023-05-17 EP disclosed
EP-3850032-B1 POLYARYLENE ETHER BASF SE (DE) 2022-05-25 EP disclosed
US-20220056216-A1 POLYARYLENE ETHER SULFONE BASF SE (DE) 2022-02-24 US disclosed
US-20220033583-A1 POLYARYLENE ETHER BASF SE (DE) 2022-02-03 US disclosed
EP-3850032-A1 POLYARYLENE ETHER BASF SE (DE) 2021-07-21 EP disclosed
EP-3850033-A1 POLYARYLENE ETHER SULFONE BASF SE (DE) 2021-07-21 EP disclosed
CN-112673051-A Poly (arylene ether) 巴斯夫欧洲公司 2021-04-16 CN disclosed
CN-112673052-A Polyarylene ether sulfones 巴斯夫欧洲公司 2021-04-16 CN disclosed
WO-2020053079-A1 POLYARYLENE ETHER BASF SE (DE) 2020-03-19 WO disclosed
WO-2020053077-A1 POLYARYLENE ETHER SULFONE BASF SE (DE) 2020-03-19 WO disclosed
WO-2003033594-A1 THERMOPLASTIC MOULDING MATERIALS BASED ON POLYARYLENE ETHER SULFONES AND POLYAMIDES BASF AKTIENGESELLSCHAFT (DE) 2003-04-24 WO disclosed
US-4152367-A RESISTANCE TO UNSATURATED POLYESTER RESINS BAYER AKTIENGESELLSCHAFT (DE) 1979-05-01 US disclosed
EP-0000732-A1 Blends of reticulated polyarylsulfones and polycarbonates and their application during the manufacture of extruded films BAYER AG (DE) 1979-02-21 EP disclosed
US-3960815-A DIELECTRICS BAYER AKTIENGESELLSCHAFT (DT) 1976-06-01 US disclosed