Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199480 | 0.85 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL10869745 | 0.85 | ALDH1A1 (0.68) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL11452192 | 0.83 | ALDH1A1 (0.60) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL2947086 | 0.83 | PTGS2 (0.49) | ALDH1A1CYP3A4MAPK1KMT2APOLB | |
| SCHEMBL8059962 | 0.79 | GAA (0.60) | ALDH1A1MEN1KMT2AFEN1KDM4E | |
| SCHEMBL2947083 | 0.79 | ALDH1A1 (0.60) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL2034446 | 0.79 | HSD11B1 (0.68) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL10585429 | 0.77 | POLB (0.56) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL4328031 | 0.77 | ALDH1A1 (1.00) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL9313173 | 0.77 | ALDH1A1 (1.00) | ALDH1A1CYP3A4MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672750-A | Preparation of aromatic amides from carbon monoxide, an amine and an aromatic chloride | EASTMAN CHEMICAL COMPANY (US) | 1997-09-30 | — | — | US | claimed |