Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | DUT | P33316 | 11/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4348697 | 0.82 | L3MBTL1 (0.59) | PKMCRBNL3MBTL1ALDH1A1LMNA | |
| SCHEMBL6102943 | 0.80 | CRBN (0.56) | PKMCRBNL3MBTL1ALDH1A1LMNA | |
| SCHEMBL12482845 | 0.78 | PKM (0.51) | PKMCRBNL3MBTL1ALDH1A1LMNA | |
| SCHEMBL4537742 | 0.78 | DUT (0.49) | PKMCRBNL3MBTL1ALDH1A1LMNA | |
| SCHEMBL15798643 | 0.76 | ENPP1 (0.51) | PKMCRBNL3MBTL1ALDH1A1LMNA | |
| SCHEMBL7231374 | 0.75 | PKM (0.53) | PKMCRBNL3MBTL1ALDH1A1LMNA | |
| SCHEMBL2990980 | 0.75 | L3MBTL1 (0.53) | PKMCRBNL3MBTL1ALDH1A1LMNA | |
| SCHEMBL23873265 | 0.74 | PKM (0.60) | PKMCRBNL3MBTL1ALDH1A1LMNA | |
| SCHEMBL8064655 | 0.74 | PKM (0.51) | PKMCRBNL3MBTL1ALDH1A1LMNA | |
| SCHEMBL1344883 | 0.74 | PKM (0.51) | PKMCRBNL3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313751-A1 | NEW MACROLIDES WITH ANTIBACTERIAL ACTIVITY | Basilea Pharmaceutica AG (CH) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002016380-A1 | NEW MACROLIDES WITH ANTIBACTERIAL ACTIVITY | BASILEA PHARMACEUTICA AG (CH) | 2002-02-28 | — | — | WO | disclosed |