Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.41 |
| ▸ | DPP4 | P27487 | 5/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23634768 | 0.82 | TAS1R3 (0.46) | DNM1CA1CA2DPP7DPP9 | |
| SCHEMBL12415210 | 0.82 | DNM1 (0.41) | DNM1CA1CA2DPP7DPP9 | |
| SCHEMBL7176520 | 0.79 | NOD1 (0.58) | CA2 | |
| SCHEMBL7176522 | 0.79 | NOD1 (0.58) | CA2 | |
| SCHEMBL7211166 | 0.77 | DNM1 (0.53) | CNR2DNM1DPP7DPP9DPP8 | |
| SCHEMBL4192033 | 0.76 | DNM1 (0.56) | DNM1DPP7PLA2G2CMEN1FAAH | |
| SCHEMBL11333450 | 0.76 | MLYCD (0.44) | CNR2DNM1CA1MEN1FAAH | |
| SCHEMBL28656099 | 0.76 | CNR2 (0.53) | CNR2CA1CA2DPP7DPP9 | |
| SCHEMBL22369854 | 0.75 | FAAH (0.47) | DNM1CA1MEN1FAAHMAPK1 | |
| SCHEMBL7208460 | 0.74 | SLC6A5 (0.60) | CNR2DNM1PLA2G2CMEN1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920434-A3 | BIS-PLATINUM COMPLEXES WITH POLYMETHYLENE DERIVATIVES AS LIGANDS HAVING ANTITUMOR ACTIVITY | F.HOFFMANN-LA ROCHE AG (CH) | 2003-06-04 | — | — | EP | disclosed |
| EP-0912584-B1 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | HOFFMANN LA ROCHE (CH) | 2002-12-18 | — | — | EP | disclosed |
| EP-0920434-B1 | BIS-PLATINUM COMPLEXES WITH POLYMETHYLENE DERIVATIVES AS LIGANDS HAVING ANTITUMOR ACTIVITY | HOFFMANN LA ROCHE (CH) | 2002-10-16 | — | — | EP | disclosed |
| US-6060616-A | ANTITUMORS AGENTS; LEUKEMIA, OVARIAN CARCINOMA | HOFFMANN-LA ROCHE INC. (US) | 2000-05-09 | — | — | US | disclosed |
| US-6022892-A | Bis-platinum complexes with polyamine ligands as antitumor agents | HOFFMAN-LA ROCHE INC. (US) | 2000-02-08 | — | — | US | disclosed |
| EP-0920434-A2 | BIS-PLATINUM COMPLEXES WITH POLYMETHYLENE DERIVATIVES AS LIGANDS HAVING ANTITUMOR ACTIVITY | F.HOFFMANN-LA ROCHE AG (CH) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998003519-A9 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | — | 1998-07-16 | — | — | WO | disclosed |
| WO-1998003518-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYMETHYLENE DERIVATIVES AS LIGANDS HAVING ANTITUMOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-29 | — | — | WO | disclosed |