Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | USP8 | P40818 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17544552 | 0.82 | HTR1A (0.43) | MAOBCTSSXDHMAPTHSD17B10 | |
| SCHEMBL3892947 | 0.82 | MAPT (0.47) | MAOBXDHMAPTHSD17B10L3MBTL1 | |
| SCHEMBL19331166 | 0.80 | SQOR (0.41) | MAOBCTSSSQORXDHSMN1; SMN2 | |
| SCHEMBL2950393 | 0.78 | MAPT (0.49) | MAOBCTSSSQORXDHMAPT | |
| SCHEMBL2951718 | 0.78 | MAPT (0.49) | MAOBCTSSXDHMAPTHSD17B10 | |
| SCHEMBL2675108 | 0.76 | LTA4H (0.58) | MAOBMAPTL3MBTL1SMN1; SMN2HTT | |
| SCHEMBL4214379 | 0.76 | LTA4H (0.58) | MAOBMAPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL26460635 | 0.76 | MAPT (0.43) | MAOBMAPTL3MBTL1SMN1; SMN2HTT | |
| SCHEMBL25679792 | 0.76 | SMN1; SMN2 (0.56) | MAPTL3MBTL1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL2950688 | 0.76 | XDH (0.40) | MAOBCTSSXDHMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2980085-B1 | PYRAZOLE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2018-03-14 | — | — | EP | disclosed |
| US-20170217980-A1 | AMLEXANOX ANALOGS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2017-08-03 | — | — | US | disclosed |
| US-20170217980-A1 | AMLEXANOX ANALOGS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2017-08-03 | — | — | US | disclosed |
| WO-2017132538-A1 | AMLEXANOX ANALOGS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-08-03 | — | — | WO | disclosed |
| US-9617240-B2 | Pyrazole derivative | TEIJIN PHARMA LIMITED (JP) | 2017-04-11 | — | — | US | disclosed |
| US-20160039784-A1 | PYRAZOLE DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2016-02-11 | — | — | US | disclosed |
| EP-2980085-A1 | PYRAZOLE DERIVATIVE | Teijin Pharma Limited (JP) | 2016-02-03 | — | — | EP | disclosed |
| CN-102015641-B | Heterocyclic compound | TAKEDA PHARMACEUTICAL | 2014-01-01 | — | — | CN | disclosed |
| US-8436043-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-05-07 | — | — | US | disclosed |
| US-20120270865-A2 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-10-25 | — | — | US | disclosed |
| US-20090156803-A1 | Condensed furan compounds | KAWAGUCHI TAKAYUKI | 2009-06-18 | — | — | US | disclosed |
| US-20090156803-A1 | Condensed furan compounds | KAWAGUCHI TAKAYUKI | 2009-06-18 | — | — | US | disclosed |
| US-20090156803-A1 | Condensed furan compounds | KAWAGUCHI TAKAYUKI | 2009-06-18 | — | — | US | disclosed |
| US-7514449-B2 | Fused furan compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7514449-B2 | Fused furan compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7514449-B2 | Fused furan compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-04-07 | — | — | US | disclosed |
| CN-100344632-C | Fused furan compound | TANABE SEIYAKU CO (JP) | 2007-10-24 | — | — | CN | disclosed |
| US-20060094724-A1 | Fused furan compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2006-05-04 | — | — | US | disclosed |
| CN-1723210-A | Fused furan compound | TANABE SEIYAKU CO (JP) | 2006-01-18 | — | — | CN | disclosed |
| EP-1582521-A1 | FUSED FURAN COMPOUND | TANABE SEIYAKU CO., LTD. (JP) | 2005-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270865-A2 | HETEROCYCLIC COMPOUND | SLC5A2, SLC5A1, IAPP | MAOB 2146/4885CTSS 4471/4885SQOR 39/4885 |
| US-20090156803-A1 | Condensed furan compounds | F2, F12, F11 | MAOB 685/4885CTSS 1395/4885SQOR 116/4885 |
| US-20160039784-A1 | PYRAZOLE DERIVATIVE | XDH, NLRP3, NLRP1 | MAOB 2373/4885CTSS 1183/4885SQOR 151/4885 |
| US-20060094724-A1 | Fused furan compound | F2, F12, F11 | MAOB 658/4885CTSS 1947/4885SQOR 172/4885 |
| US-20170217980-A1 | AMLEXANOX ANALOGS | GPR119, GLP1R, IRS1 | MAOB 4548/4885CTSS 3502/4885SQOR 2397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.