SCHEMBL7219980

SCHEMBL7219980

Cn1c(C(F)(F)F)cc(=O)n(-c2cc(OCc3cccc(OCC(=O)O)c3)c(Cl)cc2F)c1=O

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 10/20 0.40
PPARD Q03181 4/20 0.39
PPOX P50336 3/20 0.39
MRGPRX4 Q96LA9 4/20 0.38
PTGDR2 Q9Y5Y4 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7233936 0.89 LMNA (0.37) FFAR1PPARDPTGDR2
SCHEMBL7227640 0.89 MRGPRX4 (0.39) PPOXMRGPRX4PTGDR2
SCHEMBL8926019 0.87 PPOX (0.40) PPOXMRGPRX4
SCHEMBL10577900 0.87 PKM (0.40) PPARDPPOXPTGDR2
SCHEMBL10577200 0.86 PPOX (0.49) PPOXMRGPRX4
SCHEMBL7225614 0.86 MRGPRX4 (0.38) PPOXMRGPRX4
SCHEMBL7226294 0.85 FFAR1 (0.38) FFAR1PPARD
SCHEMBL7227825 0.84 TRIM24 (0.40) PPOX
SCHEMBL10579174 0.82 PPOX (0.40) FFAR1PPOXMRGPRX4
SCHEMBL3245244 0.82 BCAT1 (0.39) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6664214-B1 Uracil compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-16 US disclosed