SCHEMBL722882

SCHEMBL722882

C=C(C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NC(CC(C)C)C(=O)NCC(=O)O

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 9/20 0.51
▸ OPRM1 P35372 8/20 0.51
▸ OPRK1 P41145 4/20 0.51
▸ CTSB P07858 1/20 0.51
▸ REN P00797 1/20 0.49
▸ MMP1 P03956 1/20 0.48
▸ FCER2 P06734 1/20 0.48
▸ PSMB5 P28074 2/20 0.47
▸ MMP8 P22894 1/20 0.47
▸ MME P08473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1682420 1.00 OPRD1 (0.51) OPRD1OPRM1OPRK1CTSBREN
SCHEMBL722883 1.00 OPRD1 (0.51) OPRD1OPRM1OPRK1CTSBREN
SCHEMBL1682423 1.00 OPRD1 (0.51) OPRD1OPRM1OPRK1CTSBREN
SCHEMBL2369018 0.94 OPRD1 (0.53) OPRD1OPRM1OPRK1CTSB
SCHEMBL12295398 0.92 OPRD1 (0.54) OPRD1OPRM1OPRK1CTSBREN
SCHEMBL29250280 0.92 OPRD1 (0.52) OPRD1OPRM1OPRK1CTSBMME
SCHEMBL12808287 0.91 REN (0.55) OPRD1OPRM1OPRK1CTSBREN
SCHEMBL7259831 0.91 REN (0.55) OPRD1OPRM1OPRK1CTSBREN
SCHEMBL2369892 0.91 OPRM1 (0.53) OPRD1OPRM1OPRK1CTSBREN
SCHEMBL7773529 0.90 OPRD1 (0.51) OPRD1OPRM1OPRK1CTSBREN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10406111-B2 Gold/lanthanide nanoparticle conjugates and uses thereof COLORADO SCHOOL OF MINES (US) 2019-09-10 — — US disclosed
US-9382346-B2 Gold nanoparticle conjugates and uses thereof COLORADO SCHOOL OF MINES (US) 2016-07-05 — — US disclosed
US-20160017065-A1 Gold Nanoparticle Conjugates and Uses Thereof COLORADO SCHOOL OF MINES 2016-01-21 — — US disclosed
US-9175015-B2 Gold nanoparticle conjugates and uses thereof COLORADO SCHOOL OF MINES (US) 2015-11-03 — — US disclosed
US-20150306256-A1 Lanthanide Nanoparticle Conjugates and Uses Thereof COLORADO STATE UNIVERSITY RESEARCH FOUNDATION 2015-10-29 — — US disclosed
US-20150258034-A1 GOLD/LANTHANIDE NANOPARTICLE CONJUGATES AND USES THEREOF COLORADO SCHOOL OF MINES 2015-09-17 — — US disclosed
US-20150250902-A1 pH-RESPONSIVE GADOLINIUM NANOPARTICLE CONJUGATES AND USES THEREOF COLORADO SCHOOL OF MINES (US) 2015-09-10 — — US disclosed
US-8968705-B2 Gold/lanthanide nanoparticle conjugates and uses thereof COLORADO SCHOOL OF MINES (US) 2015-03-03 — — US disclosed
US-8916135-B2 Lanthanide nanoparticle conjugates and uses thereof COLORADO SCHOOL OF MINES (US) 2014-12-23 — — US disclosed
US-20140141089-A1 Nanoparticles, Compositions Thereof, and Methods of Use, and Methods of Making the Same COLORADO SCHOOL OF MINES (US) 2014-05-22 — — US disclosed
US-20120082728-A1 MULTIFUNCTIONAL STEALTH NANOPARTICULES FOR BIOMEDICAL USE UNIVERSITE DE STRASBOURG (FR) 2012-04-05 — — US disclosed
US-20120052006-A1 GOLD/LANTHANIDE NANOPARTICLE CONJUGATES AND USES THEREOF COLORADO SCHOOL OF MINES (US) 2012-03-01 — — US disclosed
EP-2389199-A2 MULTIFUNCTIONAL STEALTH NANOPARTICLES FOR BIOMEDICAL USE THE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2011-11-30 — — EP disclosed
WO-2010096464-A1 GOLD/LANTHANIDE NANOPARTICLE CONJUGATES AND USES THEREOF BOYES STEPHEN G (US) 2010-08-26 — — WO disclosed
WO-2010084157-A2 MULTIFUNCTIONAL STEALTH NANOPARTICLES FOR BIOMEDICAL USE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2010-07-29 — — WO disclosed
EP-2210616-A1 Multifunctional stealth nanoparticles for biomedical use Centre National de la Recherche Scientifique (FR) 2010-07-28 — — EP disclosed
US-20090060839-A1 Gold Nanoparticle Conjugates and Uses Thereof COLORADO SCHOOL OF MINES 2009-03-05 — — US disclosed
US-20090060840-A1 Lanthanide Nanoparticle Conjugates and Uses Thereof COLORADO STATE UNIVERSITY RESEARCH FOUNDATION 2009-03-05 — — US disclosed
WO-2009026540-A1 LANTHANIDE NANOPARTICLE CONJUGATES AND USES THEREOF COLORADO SCHOOL OF MINES (US) 2009-02-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150306256-A1 Lanthanide Nanoparticle Conjugates and Uses Thereof SSB, CD47, SLC6A13 OPRD1 4653/4885OPRM1 4710/4885OPRK1 4673/4885
US-20090060840-A1 Lanthanide Nanoparticle Conjugates and Uses Thereof SSB, CD47, SLC6A13 OPRD1 4653/4885OPRM1 4710/4885OPRK1 4673/4885
US-20120052006-A1 GOLD/LANTHANIDE NANOPARTICLE CONJUGATES AND USES THEREOF SSB, LGALS9, LGALS3 OPRD1 4640/4885OPRM1 4702/4885OPRK1 4654/4885
US-20140141089-A1 Nanoparticles, Compositions Thereof, and Methods of Use, and Methods of Making the Same NPC1L1, LIPA, NPC1 OPRD1 2681/4885OPRM1 2083/4885OPRK1 1493/4885
US-20150258034-A1 GOLD/LANTHANIDE NANOPARTICLE CONJUGATES AND USES THEREOF SSB, LGALS9, LGALS3 OPRD1 4640/4885OPRM1 4702/4885OPRK1 4654/4885
US-10406111-B2 Gold/lanthanide nanoparticle conjugates and uses thereof SSB, LGALS9, LGALS3 OPRD1 4640/4885OPRM1 4702/4885OPRK1 4654/4885
US-20150250902-A1 pH-RESPONSIVE GADOLINIUM NANOPARTICLE CONJUGATES AND USES THEREOF GOLGA3, GDI1, CA13 OPRD1 4845/4885OPRM1 4721/4885OPRK1 4850/4885
US-20160017065-A1 Gold Nanoparticle Conjugates and Uses Thereof CD47, SELP, SELPLG OPRD1 3853/4885OPRM1 2738/4885OPRK1 3151/4885
US-20120082728-A1 MULTIFUNCTIONAL STEALTH NANOPARTICULES FOR BIOMEDICAL USE EPHA2, CD47, MSN OPRD1 2782/4885OPRM1 985/4885OPRK1 1692/4885
US-20090060839-A1 Gold Nanoparticle Conjugates and Uses Thereof CD47, SELP, SELPLG OPRD1 3853/4885OPRM1 2738/4885OPRK1 3151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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