Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Pyrrolidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrolidine SCHEMBL28547040 | 1.00 | ALDH1A1 (0.80) | — | |
| Pyrrolidine SCHEMBL996579 | 1.00 | ALDH1A1 (0.80) | — | |
| Pyrrolidine SCHEMBL3853339 | 1.00 | ALDH1A1 (0.80) | — | |
| Pyrrolidine SCHEMBL29194307 | 0.95 | — | — | |
| Piperidine SCHEMBL7575329 | 0.95 | ALDH1A1 (0.90) | — | |
| Piperidine SCHEMBL4616564 | 0.95 | — | — | |
| Pyrrolidine SCHEMBL28458206 | 0.95 | — | — | |
| Azepane SCHEMBL20563677 | 0.95 | — | — | |
| Piperidine SCHEMBL7575332 | 0.95 | — | — | |
| Piperidine SCHEMBL781392 | 0.95 | ALDH1A1 (0.90) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112376051-A | Compound magnesium alloy corrosion inhibitor suitable for corrosion inhibition of nonferrous metals | 苏州豪尔特化工有限公司 | 2021-02-19 | — | — | CN | claimed |
| US-20020191124-A1 | Liquid crystal display device and process for producing same | NEC CORPORATION | 2002-12-19 | — | — | US | claimed |
| US-6466279-B1 | Liquid crystal display device and process for producing same in which forming first and second organic insulating layers using curing and half curing process | NEC CORPORATION (JP) | 2002-10-15 | — | — | US | claimed |
| CN-115210237-B | Dihydropyrimidine compound, preparation method and application thereof | 上海维申医药有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-113454027-B | Molecular sieve SSZ-115, synthesis and uses thereof | 雪佛龙美国公司 | 2023-06-27 | — | — | CN | disclosed |
| US-20210387949-A1 | NEW SELECTIVE MODULATORS OF INSECT NICOTINIC ACETYLCHOLINE RECEPTORS | UNIV NANTES (FR) | 2021-12-16 | — | — | US | disclosed |
| EP-3877377-A1 | NEW SELECTIVE MODULATORS OF INSECT NICOTINIC ACETYLCHOLINE RECEPTORS | Universite de Nantes (FR) | 2021-09-15 | — | — | EP | disclosed |
| EP-3650447-A1 | NEW SELECTIVE MODULATORS OF INSECT NICOTINIC ACETYLCHOLINE RECEPTORS | Universite de Nantes (FR) | 2020-05-13 | — | — | EP | disclosed |
| CN-110392607-A | Transition metal-supported zeolite, method for producing same, catalyst for nitrogen oxide purification, and method for using same | 三菱化学株式会社 | 2019-10-29 | — | — | CN | disclosed |
| CN-109415216-A | Zeolite SSZ-52x | 雪佛龙美国公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-107922384-A | Amide derivatives having multimodal activity on pain | 埃斯蒂文博士实验室股份有限公司 | 2018-04-17 | — | — | CN | disclosed |
| US-5993541-A | Process for nucleation of ceramics and product thereof | SCIENCE APPLICATIONS INTERNATIONAL CORPORATION | 1999-11-30 | — | — | US | disclosed |
| EP-0946976-A1 | AQUEOUS CLEANING SOLUTION FOR A SEMICONDUCTOR SUBSTRATE | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-10-06 | — | — | EP | disclosed |
| US-5879856-A | CONTROLLING PHOTOSPEED BY ADJUSTING AMOUNT OF LACTATE SALT PHOTOSPEED CONTROL AGENT IN PHOTORESIST COMPOSITION | SHIPLEY COMPANY, L.L.C. (US) | 1999-03-09 | — | — | US | disclosed |
| WO-1998006127-A1 | AQUEOUS CLEANING SOLUTION FOR A SEMICONDUCTOR SUBSTRATE | SIEMENS AKTIENGESELLSCHAFT (DE) | 1998-02-12 | — | — | WO | disclosed |
| EP-0783136-A2 | Chemically amplified positive photoresists | Shipley Company LLC (US) | 1997-07-09 | — | — | EP | disclosed |
| EP-0467561-B1 | Photosensitive resin composition for forming a polyimide film pattern | TOSHIBA KK (JP) | 1995-10-18 | — | — | EP | disclosed |
| US-5176982-A | Keto-silane compound | KABUSHIKI KAISHA TOSHIBA (JP) | 1993-01-05 | — | — | US | disclosed |
| EP-0467561-A2 | Photosensitive resin composition for forming a polyimide film pattern | KABUSHIKI KAISHA TOSHIBA (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4022631-A | DIMETHYL SULFOXIDE, FORMALDEHYDE | INTERNATIONAL TELEPHONE AND TELEGRAPH CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |