Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 3/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.31 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263879 | 0.86 | MAPT (0.40) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL7263916 | 0.86 | REN (0.31) | SMN1; SMN2RAB9A | |
| SCHEMBL7264513 | 0.82 | ALDH1A1 (0.40) | MAPTMEN1KMT2ASMN1; SMN2HTR7 | |
| SCHEMBL7259495 | 0.82 | LTB4R (0.36) | — | |
| SCHEMBL7259504 | 0.82 | MCHR1 (0.38) | MAPTSMN1; SMN2NPC1 | |
| SCHEMBL7451266 | 0.80 | HPGD (0.37) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7259876 | 0.80 | RAB9A (0.32) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7264021 | 0.79 | FFAR1 (0.35) | MAPTSMN1; SMN2NPC1RAB9AHTR1A | |
| SCHEMBL7264002 | 0.78 | NPC1 (0.37) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7264648 | 0.77 | BCHE (0.38) | SMN1; SMN2NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |