Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | SUCNR1 | Q9BXA5 | 5/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264002 | 0.86 | NPC1 (0.37) | MAPTNPC1LMNAPPARGPPARA | |
| SCHEMBL7264021 | 0.84 | FFAR1 (0.35) | SMN1; SMN2MAPTNPC1LMNACASP3 | |
| SCHEMBL7451266 | 0.84 | HPGD (0.37) | SMN1; SMN2LMNA | |
| SCHEMBL7259390 | 0.84 | RAB9A (0.38) | SMN1; SMN2NPC1LMNAPPARG | |
| SCHEMBL7264336 | 0.84 | FAAH (0.34) | SMN1; SMN2MAPTNPC1HDAC6 | |
| SCHEMBL7259876 | 0.83 | RAB9A (0.32) | SMN1; SMN2NPC1LMNA | |
| SCHEMBL7263916 | 0.83 | REN (0.31) | SMN1; SMN2 | |
| SCHEMBL7259380 | 0.83 | SMN1; SMN2 (0.39) | SMN1; SMN2MAPTNPC1LMNA | |
| SCHEMBL7258701 | 0.82 | MAPT (0.34) | SMN1; SMN2MAPTNPC1 | |
| SCHEMBL7259495 | 0.81 | LTB4R (0.36) | SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | disclosed |