Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259455 | 0.89 | BCHE (0.42) | BCHEMKNK1ACHESMN1; SMN2TP53 | |
| SCHEMBL7259442 | 0.88 | MAPT (0.42) | SMN1; SMN2TP53NPC1RAB9AHPGD | |
| SCHEMBL7259390 | 0.84 | RAB9A (0.38) | SMN1; SMN2TP53NPC1RAB9AHPGD | |
| SCHEMBL7264021 | 0.83 | FFAR1 (0.35) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7259504 | 0.83 | MCHR1 (0.38) | SMN1; SMN2NPC1HDAC3HDAC1HDAC2 | |
| SCHEMBL7259380 | 0.83 | SMN1; SMN2 (0.39) | SMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL7258928 | 0.82 | SMN1; SMN2 (0.34) | SMN1; SMN2TP53NPC1RAB9AHPGD | |
| SCHEMBL7264336 | 0.82 | FAAH (0.34) | SMN1; SMN2TP53NPC1RAB9AHDAC6 | |
| SCHEMBL7263111 | 0.81 | HDAC8 (0.34) | SMN1; SMN2RAB9AHDAC3HDAC1HDAC8 | |
| SCHEMBL7263916 | 0.81 | REN (0.31) | SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |