Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 7/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 5/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259018 | 0.87 | LTB4R (0.40) | LTB4RCTSACNR2ELANECNR1 | |
| SCHEMBL7258701 | 0.82 | MAPT (0.34) | — | |
| SCHEMBL7259504 | 0.81 | MCHR1 (0.38) | SUCNR1 | |
| SCHEMBL7263916 | 0.80 | REN (0.31) | — | |
| SCHEMBL7263972 | 0.80 | CNR2 (0.43) | LTB4RCTSACNR2ELANECNR1 | |
| SCHEMBL7264336 | 0.79 | FAAH (0.34) | — | |
| SCHEMBL7264021 | 0.78 | FFAR1 (0.35) | CNR2CNR1 | |
| SCHEMBL7264513 | 0.78 | ALDH1A1 (0.40) | — | |
| SCHEMBL7258928 | 0.78 | SMN1; SMN2 (0.34) | CNR1 | |
| SCHEMBL7259500 | 0.77 | LTB4R (0.36) | LTB4RCNR2ELANECNR1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | disclosed |