Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259876 | 0.87 | RAB9A (0.32) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL7264021 | 0.86 | FFAR1 (0.35) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL7259594 | 0.86 | NPC1 (0.40) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL7259504 | 0.86 | MCHR1 (0.38) | NPC1MAPTLMNAPPARGPPARA | |
| SCHEMBL7259390 | 0.82 | RAB9A (0.38) | NPC1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL7263916 | 0.82 | REN (0.31) | RAB9A | |
| SCHEMBL7262958 | 0.81 | MAPT (0.38) | POLBMEN1KMT2AMAPK1MAPT | |
| SCHEMBL7258928 | 0.81 | SMN1; SMN2 (0.34) | NPC1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL7264336 | 0.81 | FAAH (0.34) | NPC1RAB9AMAPT | |
| SCHEMBL7264648 | 0.79 | BCHE (0.38) | NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |