Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258877 | 0.90 | SMN1; SMN2 (0.40) | RAB9ANPC1SMN1; SMN2TP53MEN1 | |
| SCHEMBL7258928 | 0.88 | SMN1; SMN2 (0.34) | RAB9ANPC1SMN1; SMN2TP53MEN1 | |
| SCHEMBL7264021 | 0.86 | FFAR1 (0.35) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7259380 | 0.86 | SMN1; SMN2 (0.39) | RAB9ANPC1SMN1; SMN2TP53MEN1 | |
| SCHEMBL7264336 | 0.85 | FAAH (0.34) | RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL7259504 | 0.84 | MCHR1 (0.38) | NPC1SMN1; SMN2PPARGLMNA | |
| SCHEMBL7263111 | 0.84 | HDAC8 (0.34) | RAB9ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL7264648 | 0.84 | BCHE (0.38) | RAB9ANPC1SMN1; SMN2TP53HPGD | |
| SCHEMBL7259442 | 0.83 | MAPT (0.42) | RAB9ANPC1SMN1; SMN2TP53MEN1 | |
| SCHEMBL7264002 | 0.82 | NPC1 (0.37) | RAB9ANPC1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | disclosed |