Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | ATP4A | P20648 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259380 | 0.92 | SMN1; SMN2 (0.39) | ROCK1ALDH1A1MEN1KMT2AROCK2 | |
| SCHEMBL7264339 | 0.90 | HDAC8 (0.38) | HDAC8HDAC6HDAC1ROCK1ALDH1A1 | |
| SCHEMBL7259390 | 0.84 | RAB9A (0.38) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7259504 | 0.81 | MCHR1 (0.38) | HDAC8HDAC6HDAC1LMNASMN1; SMN2 | |
| SCHEMBL7263964 | 0.81 | SMN1; SMN2 (0.44) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7264648 | 0.81 | BCHE (0.38) | HDAC8HDAC6HDAC1SMN1; SMN2RAB9A | |
| SCHEMBL7258928 | 0.81 | SMN1; SMN2 (0.34) | MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL7259442 | 0.80 | MAPT (0.42) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7264021 | 0.80 | FFAR1 (0.35) | ALDH1A1LMNASMN1; SMN2KDM4EGAA | |
| SCHEMBL7263113 | 0.80 | ATP4A (0.35) | HDAC8HDAC6HDAC1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |