Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264648 | 0.88 | BCHE (0.38) | TP53TSHRNPC1RAB9AHPGD | |
| SCHEMBL7259390 | 0.83 | RAB9A (0.38) | TP53ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7264021 | 0.82 | FFAR1 (0.35) | MAPTALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL7259504 | 0.82 | MCHR1 (0.38) | MAPTNPC1LMNASMN1; SMN2 | |
| SCHEMBL7259380 | 0.82 | SMN1; SMN2 (0.39) | MAPTTP53ALDH1A1MAPK1KDM4E | |
| SCHEMBL7264336 | 0.81 | FAAH (0.34) | MAPTTP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7258928 | 0.81 | SMN1; SMN2 (0.34) | TP53MAPK1MEN1KMT2ANPC1 | |
| SCHEMBL7263111 | 0.80 | HDAC8 (0.34) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7264002 | 0.79 | NPC1 (0.37) | MAPTALDH1A1MAPK1POLBMEN1 | |
| SCHEMBL7258701 | 0.78 | MAPT (0.34) | MAPTALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |