Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262968 | 0.93 | SMN1; SMN2 (0.35) | SMN1; SMN2TP53NPC1RAB9AHSD17B1 | |
| SCHEMBL7259390 | 0.88 | RAB9A (0.38) | SMN1; SMN2TP53NPC1RAB9AMEN1 | |
| SCHEMBL7264336 | 0.86 | FAAH (0.34) | SMN1; SMN2TP53NPC1RAB9ASLC5A1 | |
| SCHEMBL7264021 | 0.84 | FFAR1 (0.35) | SMN1; SMN2NPC1RAB9AL3MBTL1CNR1 | |
| SCHEMBL7258741 | 0.83 | HSD17B1 (0.38) | SMN1; SMN2TP53NPC1RAB9AHSD17B1 | |
| SCHEMBL7259380 | 0.82 | SMN1; SMN2 (0.39) | SMN1; SMN2TP53NPC1RAB9AMEN1 | |
| SCHEMBL7259504 | 0.82 | MCHR1 (0.38) | SMN1; SMN2NPC1 | |
| SCHEMBL7264648 | 0.82 | BCHE (0.38) | SMN1; SMN2TP53NPC1RAB9AHPGD | |
| SCHEMBL7259442 | 0.81 | MAPT (0.42) | SMN1; SMN2TP53NPC1RAB9AMEN1 | |
| SCHEMBL7263111 | 0.81 | HDAC8 (0.34) | SMN1; SMN2RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | disclosed |