Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7260340 | 0.85 | CTSS (0.31) | CTSS | |
| SCHEMBL7260348 | 0.78 | CTSS (0.35) | CTSSALDH1A1L3MBTL1LMNAHTT | |
| SCHEMBL7255683 | 0.78 | LMNA (0.36) | CTSSALDH1A1L3MBTL1LMNAHTT | |
| SCHEMBL6633248 | 0.76 | LMNA (0.35) | CTSSALDH1A1L3MBTL1LMNAHTT | |
| SCHEMBL6630258 | 0.71 | MAPT (0.39) | — | |
| SCHEMBL6206920 | 0.70 | CTSS (0.41) | CTSSALDH1A1L3MBTL1LMNAHTT | |
| SCHEMBL7259168 | 0.70 | CTSS (0.43) | CTSSALDH1A1L3MBTL1LMNAHTT | |
| SCHEMBL6063537 | 0.70 | CTSS (0.36) | CTSSALDH1A1L3MBTL1LMNAHTT | |
| SCHEMBL6061967 | 0.69 | CTSS (0.46) | CTSS | |
| SCHEMBL6629847 | 0.69 | PTPN1 (0.38) | ALDH1A1PTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004000838-A1 | PEPTIDIC COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-12-31 | — | — | WO | disclosed |