Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268400 | 0.80 | CTSK (0.34) | POLBCNR1CNR2 | |
| SCHEMBL7268379 | 0.78 | MAPT (0.32) | POLB | |
| SCHEMBL9740788 | 0.77 | POLB (0.34) | POLB | |
| SCHEMBL7268413 | 0.75 | CTSK (0.38) | — | |
| SCHEMBL7268374 | 0.72 | REN (0.41) | — | |
| SCHEMBL7268382 | 0.69 | REN (0.46) | — | |
| SCHEMBL9741080 | 0.68 | LNPEP (0.31) | — | |
| SCHEMBL10714989 | 0.68 | LNPEP (0.32) | — | |
| SCHEMBL7782114 | 0.66 | TDP1 (0.35) | POLB | |
| SCHEMBL7782118 | 0.66 | TDP1 (0.35) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |