Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1068524 | 0.88 | TSHR (0.72) | TSHRHSD17B10HIF1ATDP1ALOX15 | |
| SCHEMBL727292 | 0.84 | TSHR (0.73) | TSHRHSD17B10HIF1ATDP1ALOX15 | |
| SCHEMBL6321695 | 0.84 | GABRA1 (0.52) | TSHRHSD17B10HIF1ATDP1ALOX15 | |
| SCHEMBL29065615 | 0.82 | TSHR (0.70) | TSHRHSD17B10HIF1ATDP1ALOX15 | |
| SCHEMBL29065613 | 0.82 | GABRA1 (0.50) | TSHRHSD17B10HIF1ATDP1ALOX15 | |
| SCHEMBL9006028 | 0.82 | ALOX15 (0.76) | TSHRHSD17B10HIF1ATDP1ALOX15 | |
| SCHEMBL18894012 | 0.79 | ALDH1A1 (0.43) | TSHRHSD17B10HIF1ATDP1ALOX15 | |
| SCHEMBL23542361 | 0.78 | ALDH1A1 (0.46) | TSHRHSD17B10HIF1ATDP1ALOX15 | |
| SCHEMBL2474087 | 0.78 | GABRA1 (0.46) | TSHRHSD17B10HIF1ATDP1ALOX15 | |
| SCHEMBL22915643 | 0.78 | CYP2C19 (0.38) | TSHRHSD17B10HIF1ATDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000108-B2 | Process for selectively polymerizing ethylene and catalyst therefor | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-04-07 | — | — | US | disclosed |
| US-9000108-B2 | Process for selectively polymerizing ethylene and catalyst therefor | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-04-07 | — | — | US | disclosed |
| US-9000108-B2 | Process for selectively polymerizing ethylene and catalyst therefor | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-04-07 | — | — | US | disclosed |
| US-20140163186-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-06-12 | — | — | US | disclosed |
| US-20140163186-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-06-12 | — | — | US | disclosed |
| US-20140163186-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-06-12 | — | — | US | disclosed |
| US-8609794-B2 | Process for selectively polymerizing ethylene and catalyst therefor | DOW GLOBAL TECHNOLOGIES, LLC. (US) | 2013-12-17 | — | — | US | disclosed |
| EP-2491062-B1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-12-11 | — | — | EP | disclosed |
| US-8273773-B2 | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC (US) | 2012-09-25 | — | — | US | disclosed |
| EP-2491062-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | Dow Global Technologies LLC (US) | 2012-08-29 | — | — | EP | disclosed |
| US-20110282018-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC | 2011-11-17 | — | — | US | disclosed |
| US-20110282018-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC | 2011-11-17 | — | — | US | disclosed |
| US-20110282018-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC | 2011-11-17 | — | — | US | disclosed |
| US-8030516-B2 | Methods for producing perfluoroalkanedi(sulfonyl chloride) | UBE INDUSTRIES, LTD. (JP) | 2011-10-04 | — | — | US | disclosed |
| US-8030516-B2 | Methods for producing perfluoroalkanedi(sulfonyl chloride) | UBE INDUSTRIES, LTD. (JP) | 2011-10-04 | — | — | US | disclosed |
| EP-2307372-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010010017-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-01-28 | — | — | WO | disclosed |
| US-20100021423-A1 | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC | 2010-01-28 | — | — | US | disclosed |
| US-20090105502-A1 | METHODS FOR PRODUCING PERFLUOROALKANEDI(SULFONYL CHLORIDE) | IM&T RESEARCH, INC. (US) | 2009-04-23 | — | — | US | disclosed |
| US-20090105502-A1 | METHODS FOR PRODUCING PERFLUOROALKANEDI(SULFONYL CHLORIDE) | IM&T RESEARCH, INC. (US) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105502-A1 | METHODS FOR PRODUCING PERFLUOROALKANEDI(SULFONYL CHLORIDE) | PFAS, PFKFB1, PFKFB2 | TSHR 686/4885HSD17B10 1233/4885HIF1A 4204/4885 |
| US-20110282018-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | WEE2, NOTUM, WEE1 | TSHR 4494/4885HSD17B10 2242/4885HIF1A 1106/4885 |
| US-20100021423-A1 | Heterocyclic antiviral compounds | POLR2A, RRM2B, RRP1B | TSHR 1823/4885HSD17B10 1679/4885HIF1A 2422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.