Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304603 | 0.73 | SIGMAR1 (0.45) | ALDH1A1LMNAGAAMAPTMAPK1 | |
| SCHEMBL7305975 | 0.71 | SIGMAR1 (0.54) | KDM4ESIGMAR1 | |
| SCHEMBL7300628 | 0.68 | MITF (0.39) | SMN1; SMN2PPARGPPARAKDM4EDRD2 | |
| SCHEMBL7304514 | 0.66 | SMN1; SMN2 (0.41) | ALDH1A1LMNAGAAMAPTMAPK1 | |
| SCHEMBL7304853 | 0.66 | SIGMAR1 (0.58) | HTR1ASIGMAR1 | |
| SCHEMBL9735887 | 0.64 | PARP1 (0.45) | PPARGPPARAHTR1ADRD3DRD2 | |
| SCHEMBL6620276 | 0.64 | DRD2 (0.57) | PPARGPPARAHTR1ADRD2DRD4 | |
| SCHEMBL7306014 | 0.63 | SIGMAR1 (0.58) | SIGMAR1PARP1 | |
| SCHEMBL4237702 | 0.63 | SIGMAR1 (0.54) | HTR1AKDM4EDRD2SIGMAR1 | |
| SCHEMBL7333358 | 0.63 | HTR1A (0.48) | ALDH1A1MAPK1HTR1AKDM4EDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149817-A | Psychotropic agents | SHIONOGI & CO., LTD. (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0445701-A1 | Novel tetrahydropyridine derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |