Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314659 | 0.95 | ALDH1A1 (0.43) | ALDH1A1KDM4EACHEKMT2ACHRM4 | |
| SCHEMBL7303568 | 0.91 | ALDH1A1 (0.45) | ALDH1A1KDM4EACHEOPRM1KMT2A | |
| SCHEMBL7306412 | 0.91 | SMN1; SMN2 (0.42) | ALDH1A1KDM4ECACNA1GACHEOPRM1 | |
| SCHEMBL7305780 | 0.88 | SMN1; SMN2 (0.43) | ALDH1A1KDM4EACHEOPRM1KMT2A | |
| SCHEMBL7314139 | 0.87 | CACNA1G (0.42) | ALDH1A1CACNA1GLMNAOPRM1OPRD1 | |
| SCHEMBL7310167 | 0.87 | CACNA1G (0.42) | ALDH1A1CACNA1GKMT2AMEN1MAPT | |
| SCHEMBL7314334 | 0.87 | CACNA1G (0.42) | ALDH1A1CACNA1GKMT2ACHRM4MEN1 | |
| SCHEMBL7307268 | 0.87 | LMNA (0.40) | CACNA1GACHELMNAOPRM1OPRD1 | |
| SCHEMBL7304933 | 0.87 | ALDH1A1 (0.40) | ALDH1A1KDM4EACHELMNAOPRM1 | |
| SCHEMBL7303592 | 0.86 | ACHE (0.42) | CACNA1GACHECHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |