Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 6/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7313830 | 0.90 | PTGDR (0.45) | PTGDRPTGDR2HTR6PPARGPPARA | |
| Trifluoroacetic Acid SCHEMBL7583561 | 0.84 | ICMT (0.37) | PTGDRPTGDR2HTR6CYP2C9CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL7307520 | 0.81 | PTGDR2 (0.38) | PTGDRPTGDR2HTR6PPARGPPARA | |
| Trifluoroacetic Acid SCHEMBL7320899 | 0.71 | SERPINE1 (0.33) | PTGDR2HTR6PPARGALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7319779 | 0.71 | HTR6 (0.55) | HTR6 | |
| Trifluoroacetic Acid SCHEMBL7310320 | 0.71 | HTR6 (0.62) | HTR6PPARGPPARAPPARD | |
| Trifluoroacetic Acid SCHEMBL7402169 | 0.69 | MTNR1A (0.38) | HTR6PPARGPPARAPPARDMTNR1A | |
| Oxalic Acid SCHEMBL7448579 | 0.69 | HTR6 (0.71) | PTGDRPTGDR2HTR6CYP2C9 | |
| Trifluoroacetic Acid SCHEMBL7318294 | 0.68 | NTSR1 (0.45) | HTR6PPARGPPARAPPARDCYP2C9 | |
| Trifluoroacetic Acid SCHEMBL7399632 | 0.66 | MTNR1A (0.36) | MTNR1AMTNR1BKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | claimed |
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | claimed |
| US-20020004198-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2002-01-10 | — | — | US | disclosed |
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | CTSL, MMP8, SERPINB1 | PTGDR 4250/4885PTGDR2 4010/4885HTR6 4503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.