Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | USP2 | O75604 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 10/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301705 | 0.86 | LMNA (0.61) | LMNAUSP2NPSR1MAPTHSD17B10 | |
| SCHEMBL7302783 | 0.85 | MAPT (0.70) | LMNAUSP2NPSR1SMN1; SMN2TSHR | |
| SCHEMBL7303413 | 0.85 | MAPT (0.49) | LMNAUSP2NPSR1SMN1; SMN2TSHR | |
| SCHEMBL7297796 | 0.84 | HTR1A (0.68) | HTR1ADRD2HTR2A | |
| SCHEMBL7306335 | 0.76 | HSD17B10 (0.56) | LMNAUSP2NPSR1SMN1; SMN2TSHR | |
| SCHEMBL7300140 | 0.74 | FABP4 (0.68) | TSHRHSD17B10HTR1ADRD2HTR2A | |
| SCHEMBL14871799 | 0.73 | AR (1.00) | ARLMNANPSR1SMN1; SMN2TSHR | |
| SCHEMBL4075010 | 0.73 | AR (0.76) | ARLMNAUSP2NPSR1SMN1; SMN2 | |
| SCHEMBL15224127 | 0.73 | AR (0.72) | ARLMNANPSR1SMN1; SMN2TSHR | |
| SCHEMBL7308089 | 0.73 | TNF (0.62) | LMNAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304560-A | Treating CNS disorders; dopamine receptor antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0481342-A1 | Quinazoline derivatives and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |