Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301822 | 0.86 | HTR1A (0.63) | HTR1AHTR7ADRA1BDRD2HTR2A | |
| SCHEMBL7308372 | 0.86 | AR (0.57) | LMNAMEN1USP2KMT2AMAPT | |
| SCHEMBL7302783 | 0.81 | MAPT (0.70) | LMNAMEN1USP2GAAKMT2A | |
| SCHEMBL7303413 | 0.81 | MAPT (0.49) | LMNAUSP2MAPTNPSR1ALDH1A1 | |
| SCHEMBL7305169 | 0.79 | HTR1A (0.61) | HTR1AHTR7ADRA1BDRD2HTR2A | |
| SCHEMBL7300518 | 0.76 | HTR7 (0.77) | MEN1KMT2AHTR1AHTR7DRD2 | |
| SCHEMBL7308089 | 0.74 | TNF (0.62) | LMNAGAAMAPTKDM4EHSD17B10 | |
| SCHEMBL7300140 | 0.71 | FABP4 (0.68) | KDM4EALDH1A1HTR1AHSD17B10DRD2 | |
| SCHEMBL7306335 | 0.70 | HSD17B10 (0.56) | LMNAMEN1USP2KMT2AMAPT | |
| SCHEMBL7297796 | 0.70 | HTR1A (0.68) | HTR1AHTR7ADRA1BDRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304560-A | Treating CNS disorders; dopamine receptor antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0481342-A1 | Quinazoline derivatives and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |