Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.78 |
| ▸ | HTR1B | P28222 | 7/20 | 0.78 |
| ▸ | HTR1D | P28221 | 7/20 | 0.78 |
| ▸ | HTR2A | P28223 | 5/20 | 0.78 |
| ▸ | HTR2C | P28335 | 4/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.78 |
| ▸ | HTR7 | P34969 | 2/20 | 0.78 |
| ▸ | HTR6 | P50406 | 2/20 | 0.78 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.78 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.78 |
| ▸ | MAPT | P10636 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.78 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331404 | 0.91 | HTR1A (0.79) | HTR1AHTR1BHTR1DHTR2AHTR2C | |
| 5-Methoxytryptamine SCHEMBL41982 | 0.88 | HTR1A (1.00) | HTR1AHTR1BHTR1DHTR2AHTR2C | |
| 5-Methoxytryptamine SCHEMBL29390103 | 0.88 | HTR1A (1.00) | HTR1AHTR1BHTR1DHTR2AHTR2C | |
| 5-Methoxytryptamine SCHEMBL130877 | 0.86 | HTR1A (0.97) | HTR1AHTR1BHTR1DHTR2AHTR2C | |
| 5-Methoxytryptamine SCHEMBL1322980 | 0.86 | NPSR1 (1.00) | HTR1AHTR1BHTR1DHTR2AHTR2C | |
| 5-Methoxytryptamine SCHEMBL31109114 | 0.86 | NPSR1 (1.00) | HTR1AHTR1BHTR1DHTR2AHTR2C | |
| 5-Methoxytryptamine SCHEMBL26617456 | 0.86 | HTR1A (0.97) | HTR1AHTR1BHTR1DHTR2AHTR2C | |
| 5-Methoxytryptamine SCHEMBL28309973 | 0.84 | HTR1A (0.91) | HTR1AHTR1BHTR1DHTR2AHTR2C | |
| 5-Methoxytryptamine SCHEMBL28681558 | 0.84 | HTR1A (0.91) | HTR1AHTR1BHTR1DHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL7313598 | 0.83 | LTA4H (0.65) | HTR1AHTR1BHTR1DHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | claimed |
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | claimed |
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | disclosed |
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | CTSL, MMP8, SERPINB1 | HTR1A 4812/4885HTR1B 4686/4885HTR1D 4756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.