Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL1335641 | 0.97 | ALDH1A1 (0.48) | ALDH1A1TDP1TSHRCA2GABRA1 | |
| Hydrochloric Acid SCHEMBL945305 | 0.95 | ALDH1A1 (0.46) | ALDH1A1TDP1TSHRCA2GABRA1 | |
| SCHEMBL29355273 | 0.78 | ALDH1A1 (0.63) | ALDH1A1TDP1TSHRCA2GABRA1 | |
| SCHEMBL580584 | 0.78 | ALDH1A1 (0.63) | ALDH1A1TDP1TSHRCA2GABRA1 | |
| SCHEMBL28606377 | 0.77 | ALDH1A1 (0.55) | ALDH1A1TDP1TSHRCA2GABRA1 | |
| SCHEMBL9594575 | 0.75 | ALDH1A1 (0.33) | ALDH1A1TDP1TSHRCA2 | |
| SCHEMBL9196196 | 0.75 | CA2 (0.70) | ALDH1A1TDP1TSHRCA2GABRA1 | |
| SCHEMBL9594550 | 0.74 | ALDH1A1 (0.32) | ALDH1A1TDP1TSHRHTT | |
| SCHEMBL8046454 | 0.74 | SHBG (0.38) | ALDH1A1TDP1TSHRPOLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31147078 | 0.73 | ALDH1A1 (0.57) | ALDH1A1TDP1TSHRCA2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293256-A1 | Remedy or preventive for kidney disease and method of diagnosing kidney disease | TORAY INDUSTRIES, INC. (JP) | 2006-12-28 | — | — | US | claimed |
| US-7004979-B2 | Dyeing composition comprising at least one diaminopyrazole oxidation base and at least one pyrazolo-azole coupling agent | L'OREAL S.A. (FR) | 2006-02-28 | — | — | US | claimed |
| EP-1550462-A1 | REMEDY OR PREVENTIVE FOR KIDNEY DISEASE AND METHOD OF DIAGNOSING KIDNEY DISEASE | TORAY INDUSTRIES, INC. (JP) | 2005-07-06 | — | — | EP | claimed |
| US-20040237220-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base and a pyrazolo-azole coupling agent | L'OREAL S.A. (FR) | 2004-12-02 | — | — | US | claimed |
| EP-0891181-B1 | KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-AZOLE COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHOD | OREAL (FR) | 2003-05-14 | — | — | EP | claimed |
| US-6551360-B2 | Pyrazoline-3,5-dione-containing compositions for dyeing keratin fibres; their use in dyeing as couplers; dyeing process | VIDAL LAURENT (FR) | 2003-04-22 | — | — | US | claimed |
| EP-0889718-B1 | KERATIN FIBRE DYE COMPOSITIONS CONTAINING PYRROLO-AZOLE COMPOUNDS, USE THEREOF AS COUPLERS, AND DYEING METHOD | OREAL (FR) | 2002-09-18 | — | — | EP | claimed |
| EP-0900074-B1 | KERATIN FIBRE DYE COMPOSITIONS CONTAINING PYRAZOLIN-3,5-DIONE COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHOD | OREAL (FR) | 2002-05-15 | — | — | EP | claimed |
| US-6379395-B1 | DYEING FOR HAIR DYE | L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | claimed |
| US-20020007523-A1 | Compositions for dyeing keratinous fibres, containing pyrazolo-azoles; their use for dyeing, as couplers; method of dyeing | L' OREAL S.A. | 2002-01-24 | — | — | US | claimed |
| US-20010054205-A1 | Pyrazoline-3, 5-dione-containing compositions for dyeing keratin fibres; their use in dyeing as couplers; dyeing process | L'OREAL | 2001-12-27 | — | — | US | claimed |
| US-20010020309-A1 | Compositions for dyeing keratinous fibres, containing pyrrolo-azoles; use as couplers; method of dyeing | L'OREAL S.A. | 2001-09-13 | — | — | US | claimed |
| US-6238440-B1 | OXIDATION-DYEING HAIR | L'OREAL S.A. (FR) | 2001-05-29 | — | — | US | claimed |
| US-6231623-B1 | OXIDATIVE DYES | L'OREAL S.A. (FR) | 2001-05-15 | — | — | US | claimed |
| EP-0888109-B1 | KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-PYRIMIDINEOXO COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHODS | OREAL (FR) | 2000-08-30 | — | — | EP | claimed |
| EP-0893985-B1 | KERATIN FIBRE DYE COMPOSITIONS CONTAINING IMIDAZOLO-AZOLE COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHOD | OREAL (FR) | 2000-04-12 | — | — | EP | claimed |
| US-4399148-A | SYSTEMIC PESTICIDES; APHIDICIDES | UNION CARBIDE CORPORATION (US) | 1983-08-16 | — | — | US | claimed |
| EP-0067503-A1 | Hydroxyaryliminoaryl carbamates, imine bisphenols and derivatives thereof useful as insecticidal compositions | UNION CARBIDE CORPORATION (US) | 1982-12-22 | — | — | EP | claimed |
| EP-2700644-B1 | NOVEL COMPOUND, NEAR-INFRARED ABSORBENT, AND SYNTHETIC RESIN COMPOSITION CONTAINING SAME | ADEKA CORP (JP) | 2015-05-20 | — | — | EP | disclosed |
| EP-0152296-A2 | Silver halide color photographic light-sensitive material | KONICA CORPORATION (JP) | 1985-08-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010054205-A1 | Pyrazoline-3, 5-dione-containing compositions for dyeing keratin fibres; their use in dyeing as couplers; dyeing process | KRT18, PYCR1, COX5A | ALDH1A1 125/4885TDP1 1903/4885TSHR 1688/4885 |
| US-20060293256-A1 | Remedy or preventive for kidney disease and method of diagnosing kidney disease | PACSIN2, CSNK2A2, CSNK2A3 | ALDH1A1 3592/4885TDP1 3045/4885TSHR 4196/4885 |
| US-20010020309-A1 | Compositions for dyeing keratinous fibres, containing pyrrolo-azoles; use as couplers; method of dyeing | KRT18, KAT7, CBR3 | ALDH1A1 944/4885TDP1 3273/4885TSHR 1356/4885 |
| US-20020007523-A1 | Compositions for dyeing keratinous fibres, containing pyrazolo-azoles; their use for dyeing, as couplers; method of dyeing | KRT18, ZYX, CBR3 | ALDH1A1 650/4885TDP1 3126/4885TSHR 1655/4885 |
| US-20040237220-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base and a pyrazolo-azole coupling agent | KRT18, PPOX, NOX5 | ALDH1A1 589/4885TDP1 610/4885TSHR 4250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.