Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 17/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324603 | 0.87 | CTSD (0.42) | CTSDREN | |
| SCHEMBL7332055 | 0.83 | CTSD (0.39) | CTSDREN | |
| SCHEMBL7329705 | 0.83 | CTSD (0.40) | CTSDCYP3A4MAPK1 | |
| SCHEMBL7324031 | 0.78 | CASP1 (0.38) | CTSD | |
| SCHEMBL7324919 | 0.76 | CYP3A4 (0.35) | CYP3A4MAPK1 | |
| SCHEMBL7328959 | 0.73 | CTSD (0.49) | CTSDREN | |
| SCHEMBL7319644 | 0.73 | CTSD (0.49) | CTSDREN | |
| SCHEMBL7329720 | 0.72 | CTSB (0.53) | CTSDREN | |
| SCHEMBL7332099 | 0.71 | LNPEP (0.37) | CTSD | |
| SCHEMBL623185 | 0.70 | CYP3A4 (0.54) | CTSDCYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |