Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327734 | 0.78 | ALOX5 (0.32) | HPGDALOX5KDM4AKDM5AKDM4C | |
| SCHEMBL7322597 | 0.76 | ALOX5 (0.33) | HPGDALOX5KDM4AKDM5AKDM4C | |
| SCHEMBL10953109 | 0.75 | LGMN (0.41) | HPGDKMT2AMEN1 | |
| SCHEMBL9754438 | 0.75 | ALOX5 (0.32) | HPGDALOX5KDM4AKDM5AKDM4C | |
| SCHEMBL9296616 | 0.73 | CA2 (0.34) | HPGDKMT2AMEN1 | |
| SCHEMBL7322813 | 0.72 | CTSD (0.37) | — | |
| SCHEMBL9754553 | 0.72 | KDM4A (0.32) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL7332099 | 0.69 | LNPEP (0.37) | HPGD | |
| SCHEMBL27899925 | 0.68 | ABCB1 (0.44) | HPGDKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7329900 | 0.68 | MMP8 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |