Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL733412 | 0.85 | RNMT (0.30) | — | |
| SCHEMBL733396 | 0.82 | ADORA3 (0.41) | PRMT5WDR77 | |
| SCHEMBL753549 | 0.81 | PRKAG1 (0.31) | P2RY12 | |
| SCHEMBL441412 | 0.78 | ADORA2A (0.35) | P2RY12 | |
| SCHEMBL2028468 | 0.77 | ADORA2B (0.38) | — | |
| SCHEMBL9539565 | 0.77 | TYMP (0.38) | PRMT5WDR77 | |
| SCHEMBL21620263 | 0.74 | PRMT6 (0.36) | P2RY12 | |
| SCHEMBL25505318 | 0.74 | PRMT6 (0.39) | P2RY12 | |
| SCHEMBL25504694 | 0.73 | ADORA1 (0.41) | — | |
| SCHEMBL5403467 | 0.73 | TRDMT1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138330-B2 | Solid phase synthesis via deblocking immobilized nucleoside, then coupling acyl protected nucleoside phosphoramidite | SIGMA-ALDRICH CO. LLC (US) | 2012-03-20 | — | — | US | disclosed |