Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2410237 | 0.85 | HAO1 (0.47) | LMNACES2CES1CASP2ALDH1A1 | |
| SCHEMBL14890831 | 0.83 | HAO1 (0.45) | LMNACES2CES1CASP2ALDH1A1 | |
| SCHEMBL21654407 | 0.83 | HAO1 (0.55) | CES2CES1TSHRALDH1A1HAO1 | |
| SCHEMBL13129296 | 0.82 | LMNA (0.46) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL23281436 | 0.81 | HAO1 (0.59) | CES2CES1TSHRALDH1A1HAO1 | |
| SCHEMBL932939 | 0.81 | HAO1 (0.59) | CES2CES1TSHRALDH1A1HAO1 | |
| SCHEMBL8577435 | 0.81 | HAO1 (0.59) | CES2CES1TSHRALDH1A1HAO1 | |
| SCHEMBL8575600 | 0.81 | HAO1 (0.59) | CES2CES1TSHRALDH1A1HAO1 | |
| SCHEMBL42695 | 0.80 | — | — | |
| SCHEMBL1701664 | 0.80 | CES2 (0.53) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230008875-A1 | SUBSTITUTED LACTAMS SHOWING SEROTONIN 5-HT RECEPTOR ACTIVITY | Sumitomo Pharma Co., Ltd. (JP) | 2023-01-12 | — | — | US | disclosed |
| US-10988571-B2 | Quorum sensing based polymer for stimulation of biofilms and related phenotypes, and synthesis process thereof | FIB-SOL Life Technologies Private Limited (IN) | 2021-04-27 | — | — | US | disclosed |
| US-10745401-B2 | Condensed lactam derivative | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-08-18 | — | — | US | disclosed |
| US-20200172543-A1 | CONDENSED LACTAM DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-06-04 | — | — | US | disclosed |
| WO-2020022237-A1 | FUSED RING LACTAM DERIVATIVES | 大日本住友製薬株式会社 | 2020-01-30 | — | — | WO | disclosed |
| US-20200031989-A1 | QUORUM SENSING BASED POLYMER FOR STIMULATION OF BIOFILMS AND RELATED PHENOTYPES, AND SYNTHESIS PROCESS THEREOF | FIB-SOL Life Technologies Private Limited (IN) | 2020-01-30 | — | — | US | disclosed |
| US-8199269-B2 | Method for manufacturing thin film transistors | HITACHI DISPLAYS, LTD. (JP) | 2012-06-12 | — | — | US | disclosed |
| EP-1208208-B1 | TRANSGENIC SYSTEMS FOR THE MANUFACTURE OF POLY(3-HYDROXY -BUTYRATE -CO -3- HYDROXYHEXANOATE) | METABOLIX INC (US) | 2009-06-17 | — | — | EP | disclosed |
| US-7455999-B2 | Transgenic systems for the manufacture of poly (3-hydroxy-butyrate-co-3-hydroxyhexanoate) | METABOLIX, INC. (US) | 2008-11-25 | — | — | US | disclosed |
| EP-0808309-A1 | IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS S-ADENOSYLMETHIONINE DECARBOXYLASE (=SAMDC) INHIBITORS | Novartis AG (CH) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996022979-A1 | IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS S-ADENOSYLMETHIONINE DECARBOXYLASE (=SAMDC) INHIBITORS | NOVARTIS AG (CH) | 1996-08-01 | — | — | WO | disclosed |
| WO-1996016980-A1 | MORPHOLINOETHYLAMIDE DERIVATIVES | NOVARTIS AG (CH) | 1996-06-06 | — | — | WO | disclosed |
| EP-0708760-A1 | CYCLIC HYDRAZINE COMPOUNDS | Novartis AG (CH) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002582-A1 | CYCLIC HYDRAZINE COMPOUNDS | CIBA-GEIGY AG (CH) | 1995-01-26 | — | — | WO | disclosed |
| EP-0114059-B1 | METHOD OF PREPARING A POLYAMIDE ACID COMPOSITION FOR PREPARING POLYIMIDE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-06-14 | — | — | EP | disclosed |
| EP-0083690-B1 | POLYAMIDE ACID COMPOSITION FOR PREPARING POLYIMIDE AND PROCESS FOR PREPARING POLYIMIDE FROM THE SAME | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-03-12 | — | — | EP | disclosed |
| US-4515915-A | Polyamide acid composition for preparing polyimide | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-05-07 | — | — | US | disclosed |
| EP-0114059-A2 | Method of preparing a polyamide acid composition for preparing polyimide | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-07-25 | — | — | EP | disclosed |
| US-4454276-A | POT LIFE EXTENDING AGENT | Kanegafuchi Chkagaku Kogyo Kabushiki Kaisha (JP) | 1984-06-12 | — | — | US | disclosed |
| EP-0083690-A1 | Polyamide acid composition for preparing polyimide and process for preparing polyimide from the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10988571-B2 | Quorum sensing based polymer for stimulation of biofilms and related phenotypes, and synthesis process thereof | PGLS, COASY, FDPS | HDAC3 4261/4885HDAC1 4529/4885HDAC2 4821/4885 |
| US-10745401-B2 | Condensed lactam derivative | PSEN1, GRIN1, HDAC1 | HDAC3 123/4885HDAC1 3/4885HDAC2 15/4885 |
| US-20230008875-A1 | SUBSTITUTED LACTAMS SHOWING SEROTONIN 5-HT RECEPTOR ACTIVITY | HTR1A, HTR5A, TPH1 | HDAC3 2410/4885HDAC1 715/4885HDAC2 1320/4885 |
| US-20200172543-A1 | CONDENSED LACTAM DERIVATIVE | PSEN1, GRIN1, HDAC1 | HDAC3 123/4885HDAC1 3/4885HDAC2 15/4885 |
| US-20200031989-A1 | QUORUM SENSING BASED POLYMER FOR STIMULATION OF BIOFILMS AND RELATED PHENOTYPES, AND SYNTHESIS PROCESS THEREOF | PGLS, COASY, FDPS | HDAC3 4261/4885HDAC1 4529/4885HDAC2 4821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.