Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373291 | 0.89 | PLA2G4A (0.40) | LOXL2ALDH1A1PLA2G4ACES1SLC7A5 | |
| SCHEMBL7374711 | 0.89 | ALDH1A1 (0.44) | ALDH1A1PLA2G4AACACBCES1F2 | |
| SCHEMBL7369216 | 0.80 | GABRP (0.46) | ALDH1A1PLA2G4ACES1F2SLC7A5 | |
| SCHEMBL7371771 | 0.76 | CPB2 (0.39) | ALDH1A1PLA2G4ACES1CMA1MMP2 | |
| SCHEMBL7377556 | 0.75 | ALDH1A1 (0.43) | ALDH1A1PLA2G4ACES1F2 | |
| SCHEMBL27699627 | 0.74 | ALDH1A1 (0.50) | ALDH1A1PLA2G4ACES1 | |
| SCHEMBL7375810 | 0.74 | GSR (0.43) | ALDH1A1PLA2G4ACES1F2MMP2 | |
| Phenylalanine SCHEMBL367780 | 0.73 | SLC7A5 (0.61) | ALDH1A1PLA2G4ACES1SLC7A5ALPI | |
| SCHEMBL8800894 | 0.73 | ALDH1A1 (0.44) | ALDH1A1PLA2G4ACES1F2KMT2A | |
| SCHEMBL4525027 | 0.72 | ALDH1A1 (0.38) | ALDH1A1PLA2G4ACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057314-A | ANTICOAGULANTS | BIOCHEM PHARMA INC. (CA) | 2000-05-02 | — | — | US | disclosed |
| CN-1175259-A | Low molecular weight bicyclic thrombin inhibitors | IAF BIOCHEM INT (CA) | 1998-03-04 | — | — | CN | disclosed |
| WO-1996019483-A1 | LOW MOLECULAR WEIGHT BICYCLIC THROMBIN INHIBITORS | BIOCHEM PHARMA INC. (CA) | 1996-06-27 | — | — | WO | disclosed |