Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.45 |
| ▸ | CTSB | P07858 | 5/20 | 0.42 |
| ▸ | CTSL | P07711 | 4/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | CTSH | P09668 | 1/20 | 0.42 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.41 |
| ▸ | CTRL | P40313 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.41 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.41 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.41 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028324 | 0.81 | CTSL (0.51) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL6448550 | 0.79 | CTSS (0.67) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL8690335 | 0.78 | CTSS (0.46) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL7545314 | 0.77 | CTSS (0.62) | CTSSCTSBCTSLCTSC | |
| SCHEMBL7412388 | 0.76 | CTSS (0.42) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL7546891 | 0.72 | CTSS (0.60) | CTSSCTSBCTSLCTSCALDH1A1 | |
| SCHEMBL6450679 | 0.72 | CTSB (0.38) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL30747838 | 0.72 | CTSS (0.68) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL7445245 | 0.72 | ALDH1A1 (0.57) | ALDH1A1CYP3A4 | |
| SCHEMBL7413210 | 0.71 | CTSL (0.57) | CTSSCTSBCTSLCTSKCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020107266-A1 | Compounds, compositions and methods for treatment of parasitic infections | DENDREON CORPORATION | 2002-08-08 | — | — | US | claimed |
| WO-2002048097-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF PARASITIC INFECTIONS | CORVAS INTERNATIONAL, INC. (US) | 2002-06-20 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107266-A1 | Compounds, compositions and methods for treatment of parasitic infections | CAT, CTSA, CTRL | CTSS 5/4885CTSB 6/4885CTSL 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.