Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GRN | P28799 | 2/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424802 | 0.88 | ALDH1A1 (0.36) | L3MBTL1RAB9ANPC1MAPK1ECE1 | |
| SCHEMBL7426234 | 0.86 | LOXL2 (0.47) | L3MBTL1RAB9ANPC1MAPK1NR4A2 | |
| SCHEMBL7425594 | 0.85 | LOXL2 (0.46) | L3MBTL1RAB9AMAPK1HDAC3HDAC4 | |
| SCHEMBL7417819 | 0.84 | HDAC1 (0.34) | TDP1GRNSORT1HDAC1HDAC6 | |
| SCHEMBL7422281 | 0.81 | SHMT1 (0.39) | L3MBTL1GRNSORT1MAPTLMNA | |
| SCHEMBL7425006 | 0.80 | NR4A2 (0.36) | GRNSORT1NR4A2 | |
| SCHEMBL7424356 | 0.79 | HDAC1 (0.36) | L3MBTL1RAB9AGRNSORT1HDAC1 | |
| SCHEMBL7419478 | 0.78 | MMP2 (0.42) | GRNSORT1CNR2ALDH1A1LMNA | |
| SCHEMBL7423853 | 0.76 | PPARA (0.35) | GRNSORT1NR4A2 | |
| SCHEMBL7422595 | 0.75 | RXRA (0.40) | GRNSORT1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |