Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | PLAU | P00749 | 2/20 | 0.59 |
| ▸ | MASP2 | O00187 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.56 |
| ▸ | F2 | P00734 | 4/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 2/20 | 0.55 |
| ▸ | F12 | P00748 | 1/20 | 0.55 |
| ▸ | F7 | P08709 | 1/20 | 0.55 |
| ▸ | F3 | P13726 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5189332 | 0.97 | PRSS1 (0.61) | LMNAPLAUMASP2THPOPRSS1 | |
| SCHEMBL537030 | 0.85 | LMNA (0.77) | LMNAPLAUMASP2THPOPRSS1 | |
| Hydrochloric Acid SCHEMBL392375 | 0.82 | PRSS1 (0.78) | LMNAPLAUMASP2THPOPRSS1 | |
| Hydrochloric Acid SCHEMBL30999366 | 0.82 | PRSS1 (0.78) | LMNAPLAUMASP2THPOPRSS1 | |
| SCHEMBL394218 | 0.77 | WDR5 (0.80) | LMNAPLAUMASP2THPOPRSS1 | |
| SCHEMBL8973288 | 0.77 | WDR5 (0.80) | LMNAPLAUMASP2THPOPRSS1 | |
| SCHEMBL6588885 | 0.74 | LMNA (0.62) | LMNAPLAUMASP2THPOPRSS1 | |
| Hydrochloric Acid SCHEMBL29182280 | 0.74 | PRSS1 (0.67) | LMNAPLAUMASP2THPOPRSS1 | |
| SCHEMBL563315 | 0.74 | LMNA (1.00) | LMNAPLAUMASP2THPOPRSS1 | |
| SCHEMBL150756 | 0.74 | PLAU (1.00) | LMNAPLAUMASP2THPOPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11541010-B2 | Amphoteric liposomes comprising imino lipids | BIONTECH DELIVERY TECHNOLOGIES GMBH (DE) | 2023-01-03 | — | — | US | disclosed |
| US-20200330384-A1 | AMPHOTERIC LIPOSOMES COMPRISING IMINO LIPIDS | BIONTECH DELIVERY TECHNOLOGIES GMBH (DE) | 2020-10-22 | — | — | US | disclosed |
| WO-2020154431-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | LYNCH KEVIN R (US) | 2020-07-30 | — | — | WO | disclosed |
| US-10039714-B2 | Imino compounds for amphoteric liposomes and uses thereof | NOVOSOM VERWALTUNGS GMBH (DE) | 2018-08-07 | — | — | US | disclosed |
| US-9523031-B2 | Organic electroluminescent device | IDEMITSU KOSAN CO., LTD. (JP) | 2016-12-20 | — | — | US | disclosed |
| US-9523031-B2 | Organic electroluminescent device | IDEMITSU KOSAN CO., LTD. (JP) | 2016-12-20 | — | — | US | disclosed |
| EP-2806873-B1 | AMIDINE SUBSTITUTED BETA-LACTAM COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS | AICURIS GMBH & CO KG (DE) | 2016-06-15 | — | — | EP | disclosed |
| WO-2010051530-A2 | COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET | THE GENERAL HOSPITAL CORPORATION (US) | 2010-05-06 | — | — | WO | disclosed |
| WO-2009058278-A1 | METHODS OF CLEANING SEMICONDUCTOR DEVICES AT THE BACK END OF LINE USING AMIDOXIME COMPOSITIONS | EKC TECHNOLOGY, INC (US) | 2009-05-07 | — | — | WO | disclosed |
| US-20070224448-A1 | Organic Electroluminescent Device | IDEMITSU KOSAN CO., LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
| US-20070224448-A1 | Organic Electroluminescent Device | IDEMITSU KOSAN CO., LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
| CN-1220681-C | Indole derivatives as XA factor inhibitors | AVENTIS MEDICINES DEUTSCHLAND (DE) | 2005-09-28 | — | — | CN | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| CN-1283186-A | Indole derivatives as XA factor inhibitors | AWENTIS MEDICINES DEUTSCHLAND (DE) | 2001-02-07 | — | — | CN | disclosed |
| EP-1042287-A1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | Aventis Pharma Deutschland GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| CN-1243505-A | Benzamidine derivatives | AJINOMOTO KK (JP) | 2000-02-02 | — | — | CN | disclosed |
| WO-1999033800-A1 | INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |
| EP-0409634-A2 | Liquid crystal compounds and optically active compounds | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11541010-B2 | Amphoteric liposomes comprising imino lipids | SGMS1, SGMS2, PHOSPHO1 | LMNA 64/4885PLAU 1673/4885MASP2 2353/4885 |
| US-10039714-B2 | Imino compounds for amphoteric liposomes and uses thereof | IPO8, IPO7, PHOSPHO1 | LMNA 53/4885PLAU 1154/4885MASP2 2464/4885 |
| US-20200330384-A1 | AMPHOTERIC LIPOSOMES COMPRISING IMINO LIPIDS | SGMS1, SGMS2, PHOSPHO1 | LMNA 64/4885PLAU 1673/4885MASP2 2353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.